Evidence map›Paper›PMID 32967905›Full record

ArticleJournal of clinical microbiology2020

A Novel Platform Using RNA Signatures To Accelerate Antimicrobial Susceptibility Testing in Neisseria gonorrhoeae.

Marjan M Hashemi, Nikhil Ram-Mohan, Xi Yang, Nadya Andini, Nicholas R Gessner, Karen C Carroll, Tza-Huei Wang, Samuel Yang

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Biographical Feature: Karen C. Carroll, M.D.Journal of clinical microbiology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Marjan M HashemiDepartment of Emergency Medicine, Stanford University, Stanford, California, USA.ORCID 0000-0003-4402-4410
Nikhil Ram-MohanDepartment of Emergency Medicine, Stanford University, Stanford, California, USA.
Xi YangDepartment of Emergency Medicine, Stanford University, Stanford, California, USA.
Nadya AndiniDepartment of Emergency Medicine, Stanford University, Stanford, California, USA.
Nicholas R GessnerDepartment of Emergency Medicine, Stanford University, Stanford, California, USA.
Karen C CarrollDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland, USA.
Tza-Huei WangDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Samuel YangDepartment of Emergency Medicine, Stanford University, Stanford, California, USA syang5@stanford.edu.ORCID 0000-0003-1123-9036

Funding

Technology development for point-of-care detection and antimicrobial susceptibility testing of Neisseria gonorrhoeaeR01AI138978 · NIAID · JOHNS HOPKINS UNIVERSITY · PI WANG, TZA-HUEI JEFF · 2018 to 2021
$5.1M
A "Culture" Shift: Integrated Bacterial Screening and Antibacterial Susceptibility Test on Microfluidic Digital Array for Bloodstream InfectionsR01AI137272 · NIAID · JOHNS HOPKINS UNIVERSITY · PI WANG, TZA-HUEI JEFF, YANG, SAMUEL · 2018 to 2022
$3.6M
NIAID NIH HHS R01 AI137272NIAID NIH HHS R01 AI138978
6 · The paper itself

Abstract

The rise of antimicrobial-resistant pathogens can be attributed to the lack of a rapid pathogen identification (ID) or antimicrobial susceptibility testing (AST), resulting in delayed therapeutic decisions at the point of care. Gonorrhea is usually empirically treated, with no AST results available before treatment, thus contributing to the rapid rise in drug resistance. Here, we present a rapid AST platform using RNA signatures for

Indexed as

GonorrheaNeisseria gonorrhoeaeAnti-Bacterial AgentsAzithromycinDrug Resistance, BacterialHumansMicrobial Sensitivity TestsReproducibility of ResultsRNAAnti-Bacterial AgentsAzithromycinRNAantimicrobial susceptibility testingazithromycinNeisseria gonorrhoeaeRNA markersRNA-seq

Identifiers

PMID32967905
PMCPMC7685871

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.