Evidence map›Paper›PMID 32968829›Full record

ReviewPharmaceutical research2020

Stimuli-Responsive Insulin Delivery Devices.

Stephanie Fuchs, Kaavian Shariati, Minglin Ma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephanie FuchsDepartment of Biological and Environmental Engineering, Cornell University, 332 Riley Robb Hall 332, Ithaca, New York, 14853, USA.
Kaavian ShariatiDepartment of Biological and Environmental Engineering, Cornell University, 332 Riley Robb Hall 332, Ithaca, New York, 14853, USA.
Minglin MaDepartment of Biological and Environmental Engineering, Cornell University, 332 Riley Robb Hall 332, Ithaca, New York, 14853, USA. mm826@cornell.edu.ORCID http://orcid.org/0000-0002-9553-7526
Cornell University · US

Funding

Foundation for the National Institutes of Health 1R01DK105967-01A1National Science Foundation SNM-1530522
6 · The paper itself

Abstract

The development of new diabetes treatment strategies has garnered much interest given that conventional management therapies for type 1 diabetes fail to provide optimal glycemic control while creating a high burden of self-care to patients. Stimuli-responsive, "closed-loop" systems are particularly attractive due to their ability to mimic dynamic ß cell function by releasing insulin in response to fluctuating glucose levels in real-time and with minimal patient discomfort. In this short review, we focus on stimuli-responsive, reservoir-based insulin delivery devices. We explore and evaluate systems that are either physiologically or externally triggered. While obstacles remain before such technologies can be translated to clinical settings, further optimization of delivery systems forebodes that these technologies will have a tremendous impact on type 1 diabetes treatment.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 1Drug CarriersDrug Delivery SystemsHumansInsulinInsulin Infusion SystemsStimuli Responsive PolymersBlood GlucoseDrug CarriersInsulinStimuli Responsive Polymersclosed-loop devicesdrug deliverystimuli-responsivetype 1 diabetes

Identifiers

PMID32968829
OpenAlexW3088791240

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.