Evidence map›Paper›PMID 32983137›Full record

ReviewFrontiers in immunology2020

Phage Display Derived Monoclonal Antibodies: From Bench to Bedside.

Mohamed A Alfaleh, Hashem O Alsaab, Ahmad Bakur Mahmoud, Almohanad A Alkayyal, Martina L Jones, Stephen M Mahler, Anwar M Hashem

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 267 citations in OpenAlex.

  1. Computationally Evidence-Grounded Sequence-First Design of Peptide Binders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Generative AI-drivenAntibody therapeutics · 2026
    Article
  4. In Vitro Selection of Antibodies TargetingPathogens (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. ImmTAC: A Novel Platform of T-Cell Receptor-Based Soluble Bispecifics.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Technologies for Monoclonal Antibody Discovery and Development.International journal of molecular sciences · 2025
    Review

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Mohamed A AlfalehFaculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Hashem O AlsaabDepartment of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Taif University, Taif, Saudi Arabia.
Ahmad Bakur MahmoudCollege of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia.
Almohanad A AlkayyalDepartment of Medical Laboratory Technology, University of Tabuk, Tabuk, Saudi Arabia.
Martina L JonesAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, Australia.
Stephen M MahlerAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, Australia.
Anwar M HashemVaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
King Abdulaziz University · SAUniversity of Queensland · AUTaibah University · SATaif University · SAUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoclonal antibodies (mAbs) have become one of the most important classes of biopharmaceutical products, and they continue to dominate the universe of biopharmaceutical markets in terms of approval and sales. They are the most profitable single product class, where they represent six of the top ten selling drugs. At the beginning of the 1990s, an

Indexed as

Antibodies, MonoclonalCell Surface Display TechniquesAnimalsAntibody SpecificityAntineoplastic Agents, ImmunologicalClinical Trials as TopicDrug DevelopmentDrug Evaluation, PreclinicalGenetic EngineeringHigh-Throughput Screening AssaysHumansMolecular Targeted TherapyTranslational Research, BiomedicalTreatment OutcomeAntibodies, MonoclonalAntineoplastic Agents, Immunologicalantibody librariesbiopanningbiopharmaceuticalsmonoclonal antibodiesphage display

Identifiers

PMID32983137
PMCPMC7485114
OpenAlexW3044690826

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.