Evidence map›Paper›PMID 32991818›Full record

Trial reportGut microbes2020

Effects of fecal microbiota transplantation in subjects with irritable bowel syndrome are mirrored by changes in gut microbiome.

Rasmus Goll, Peter Holger Johnsen, Erik Hjerde, Joseph Diab, Per Christian Valle, Frank Hilpusch, Jorunn Pauline Cavanagh

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Trial
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  12. Review
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  15. Article
  16. Advances in Fecal Microbiota Transplantation for Gut Dysbiosis-Related Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rasmus GollResearch Group of Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Arctic University of Norway , Tromsø, Norway.ORCID 0000-0003-4375-0509
Peter Holger JohnsenResearch Group of Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Arctic University of Norway , Tromsø, Norway.ORCID 0000-0001-6570-7347
Erik HjerdeInstitute of Chemistry, UiT the Arctic University of Norway , Tromsø, Norway.ORCID 0000-0002-6014-1249
Joseph DiabNatural Products and Medicinal Chemistry Research Group, Department of Pharmacy, UiT the Arctic University of Norway , Tromsø, Norway.ORCID 0000-0001-9170-4967
Per Christian ValleDepartment of Internal Medicine, University Hospital of North Norway , Harstad, Norway.ORCID 0000-0002-4060-1850
Frank HilpuschSjøkanten Legesenter , Harstad, Norway.
Jorunn Pauline CavanaghPediatric Infections Group. Department of Pediatrics, University Hospital of North Norway , Tromsø, Norway.ORCID 0000-0003-2058-1431
University Hospital of North Norway · NOUiT The Arctic University of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a common disorder of the lower gastrointestinal tract. The pathophysiology is far from settled, but a gut microbial dysbiosis is hypothesized to be a contributing factor. We earlier published a randomized double-blind placebo-controlled clinical trial on fecal microbiota transplantation (FMT) for IBS - the REFIT trial. The present data set describes the engraftment and includes participants from the study who received active FMT; 14 participants with effect of FMT (

Indexed as

Fecal Microbiota TransplantationGastrointestinal MicrobiomeAdultAgedBacteriaDouble-Blind MethodFemaleHumansIrritable Bowel SyndromeMaleMiddle AgedTissue DonorsTreatment OutcomeYoung Adultdiversityengraftmentfecal microbiota transplantationfunctional featuresgrowth rateIrritable bowel syndromemetagenomic sequencingtaxonomic profile

Identifiers

PMID32991818
PMCPMC7583512
OpenAlexW3090626432

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.