Evidence map›Paper›PMID 32995676›Full record

ArticleBioactive materials2021

Stepwise 3D-spatio-temporal magnesium cationic niche: Nanocomposite scaffold mediated microenvironment for modulating intramembranous ossification.

Jie Shen, Bo Chen, Xinyun Zhai, Wei Qiao, Shuilin Wu, Xuanyong Liu, Ying Zhao, Changshun Ruan, Haobo Pan, Paul K Chu and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  10. Bioactive elements manipulate bone regeneration.Biomaterials translational · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Jie ShenDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Bo ChenDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Xinyun ZhaiSchool of Materials Science and Engineering, Nankai University, Tianjin, China.
Wei QiaoDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Shuilin WuSchool of Materials Science & Engineering, the Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, China.
Xuanyong LiuState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China.
Ying ZhaoCenter for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Changshun RuanCenter for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Haobo PanCenter for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Paul K ChuDepartment of Physics, Department of Materials Science & Engineering, and Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.
Kenneth M C CheungDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Kelvin W K YeungDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Chinese Academy of Sciences · CNUniversity of Hong Kong - Shenzhen Hospital · CNCity University of Hong Kong · HKNankai University · CNRuijin Hospital · CNTianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fate of cells and subsequent bone regeneration is highly correlated with temporospatial coordination of chemical, biological, or physical cues within a local tissue microenvironment. Deeper understanding of how mammalian cells react to local tissue microenvironment is paramount important when designing next generation of biomaterials for tissue engineering. This study aims to investigate that the regulation of magnesium cationic (Mg

Indexed as

3D scaffoldBone tissue regenerationMagnesium ionMicroenvironmentNanocomposite

Identifiers

PMID32995676
PMCPMC7492774
OpenAlexW3085546928

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.