Evidence mapPaperPMID 32998697Full record

SynthesisBMC anesthesiology2020

Effects of electroencephalography and regional cerebral oxygen saturation monitoring on perioperative neurocognitive disorders: a systematic review and meta-analysis.

Lin Ding, Dong Xu Chen, Qian Li

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC anesthesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07339449 (Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study), which is not on this map. Cited by 29 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 5 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07339449 narecruitingnot on this mapstarted 2025, after this paper: background citation

Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study

TypeinterventionalSponsorUniversity Hospital DubravaRan2025 to 2027Enrolled100ConditionsMajor Abdominal Surgeries, Mechanical VentilationArmsMultimodal monitoring
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  5. Pooled it
  6. Trial
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  11. Observational
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  15. A screening for cerebral deoxygenation during VT ablations in patients with structural heart disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  16. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  17. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  18. Brain health: A concern for anaesthesiologists and intensivists.European journal of anaesthesiology and intensive care · 2024
    Review
  19. Article
  20. Postoperative cognitive dysfunction: a concept analysis.Aging clinical and experimental research · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lin DingNational Clinical Research Center for Geriatrics and department of Anesthesiology, West China Hospital of Sichuan University & The Research Units of West China (2018RU012), Chinese Academy of Medical Sciences, Chengdu, 610041, China.
Dong Xu ChenNational Clinical Research Center for Geriatrics and department of Anesthesiology, West China Hospital of Sichuan University & The Research Units of West China (2018RU012), Chinese Academy of Medical Sciences, Chengdu, 610041, China.
Qian LiNational Clinical Research Center for Geriatrics and department of Anesthesiology, West China Hospital of Sichuan University & The Research Units of West China (2018RU012), Chinese Academy of Medical Sciences, Chengdu, 610041, China. sculiqian@foxmail.com.ORCID 0000-0003-3301-4284
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Qian li Z2018A10
6 · The paper itself

Abstract

backgroundPerioperative neurocognitive disorders (PND) is a common postoperative complication including postoperative delirium (POD), postoperative cognitive decline (POCD) or delayed neurocognitive recovery. It is still controversial whether the use of intraoperative cerebral function monitoring can decrease the incidence of PND. The purpose of this study was to evaluate the effects of different cerebral function monitoring (electroencephalography (EEG) and regional cerebral oxygen saturation (rSO

methodsThe electronic databases of Ovid MEDLINE, PubMed, EMBASE, Cochrane Library database were systematically searched using the indicated keywords from their inception to April 2020. The odds ratio (OR) or mean difference (MD) with 95% confidence interval (CI) were employed to analyze the data. Heterogeneity across analyzed studies was assessed with chi-square test and I

resultsTwenty two RCTs with 6356 patients were included in the final analysis. Data from 12 studies including 4976 patients were analyzed to assess the association between the EEG-guided anesthesia and PND. The results showed that EEG-guided anesthesia could reduce the incidence of POD in patients undergoing non-cardiac surgery (OR: 0.73; 95% CI: 0.57-0.95; P = 0.02), but had no effect on patients undergoing cardiac surgery (OR: 0.44; 95% CI: 0.05-3.54; P = 0.44). The use of intraoperative EEG monitoring reduced the incidence of POCD up to 3 months after the surgery (OR: 0.69; 95% CI: 0.49-0.96; P = 0.03), but the incidence of early POCD remained unaffected (OR: 0.61; 95% CI: 0.35-1.07; P = 0.09). The remaining 10 studies compared the effect of rSO

conclusionsThe findings in the present study indicated that intraoperative use of EEG or/and rSO

trial registrationPROSPREO registration number: CRD42019130512 .

Indexed as

Monitoring, IntraoperativeAnesthesiaBrainDeliriumElectroencephalographyHumansNeurocognitive DisordersOxygenPostoperative ComplicationsOxygenElectroencephalographyPerioperative neurocognitive disordersPostoperative cognitive declinePostoperative deliriumRegional cerebral oxygen saturation

Identifiers

PMID32998697
PMCPMC7526409
OpenAlexW3090945902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.