ArticleScientific reports2020
Liver and spleen elastography of dogs affected by brachycephalic obstructive airway syndrome and its correlation with clinical biomarkers.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Association of brachycephaly, sleep-disordered breathing, and inflammatory response in dogs.Journal of veterinary internal medicine · 2026Review
- Ultrasonographic and elastographic findings of the liver of dogs exposed to cigarette smoke.Brazilian journal of veterinary medicine · 2026Article
- Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome.Scientific reports · 2025Article
- Elastographic and ultrasound findings of the dog`s kidneys exposed to cigarette smoke.Brazilian journal of veterinary medicine · 2025Article
- BOAS in the Boston Terrier: A healthier screw-tailed breed?PloS one · 2024Article
- B-mode ultrasonography and ARFI elastography of articular and peri-articular structures of the hip joint in non-dysplastic and dysplastic dogs as confirmed by radiographic examination.BMC veterinary research · 2023Article
- Thrombocytosis in brachycephalic dogs with brachycephalic obstructive airway syndrome.Veterinarni medicina · 2023Article
- Brachycephalic obstructive airway syndrome: much more than a surgical problem.The veterinary quarterly · 2022Review
- Shear wave elastography measurements in dogs treated surgically for congenital extrahepatic portosystemic shunts.Frontiers in veterinary science · 2022Article
- Two-dimensional shear wave elastography of liver in healthy dogs: anaesthesia as a source of variability.International journal of veterinary science and medicine · 2022Article
- The Need for Head Space: Brachycephaly and Cerebrospinal Fluid Disorders.Life (Basel, Switzerland) · 2021Review
- Description of a novel method for detection of sleep-disordered breathing in brachycephalic dogs.Journal of veterinary internal medicineArticle
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study is to determine whether the brachycephalic obstructive airway syndrome (BOAS) is correlated to alterations in liver and spleen elasticity. Forty-eight brachycephalic and 22 mesocephalic dogs were submitted to a BOAS functional assessment, laboratory tests, abdominal ultrasound and liver and spleen Acoustic Radiation Force Impulse (ARFI) elastography. Dogs clinically affected by BOAS had higher values of liver stiffness (p < 0.001) than healthy dogs: medial lobes (1.57 ± 0.37 m/s), left and right lateral lobes (1.54 ± 0.50 m/s, 1.23 ± 0.28 m/s, respectively) and caudate lobe (1.28 ± 0.42 m/s). Compared to the mesocephalic group, the brachycephalic group (BOAS clinically affected and unaffected dogs) had higher spleen (2.51 ± 0.45 m/s; p < 0.001) and liver stiffness (p < 0.001): medial lobes (1.53 ± 0.37 m/s), left and right lateral lobes (1.47 ± 0.47 m/s, 1.20 ± 0.30 m/s, respectively) and caudate lobe (1.23 ± 0.40 m/s). Principal component analysis explained 70% of the variances composed by liver stiffness increase, erythrocytes and alanine aminotransferase reduction. Brachycephalic dogs had higher spleen and liver stiffness and a subacute inflammatory state, which represent another BOAS systemic effect. Consequently, these dogs can be at higher risk of hepatic disorders compared with mesocephalic dogs, similarly to humans affected by sleep apnea syndrome.
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