Evidence map›Paper›PMID 33002760›Full record

ArticleRedox biology2020

Green tea polyphenolic antioxidants oxidize hydrogen sulfide to thiosulfate and polysulfides: A possible new mechanism underpinning their biological action.

Kenneth R Olson, Austin Briggs, Monesh Devireddy, Nicholas A Iovino, Nicole C Skora, Jenna Whelan, Brian P Villa, Xiaotong Yuan, Varun Mannam, Scott Howard and 3 more

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

  1. Silver Tip (International journal of molecular sciences · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Reaction Mechanisms of HAntioxidants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Novel HRSC advances · 2023
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Naphthoquinones Oxidize HInternational journal of molecular sciences · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Kenneth R OlsonIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA. Electronic address: olson.1@nd.edu.
Austin BriggsIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
Monesh DevireddyIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA.
Nicholas A IovinoIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
Nicole C SkoraIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
Jenna WhelanIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
Brian P VillaIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
Xiaotong YuanDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Varun MannamDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Scott HowardDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Yan GaoIndiana University School of Medicine - South Bend, South Bend, IN, 46617, USA.
Magdalena MinnionNIHR Southampton Biomedical Research Center, University of Southampton, Southampton, General Hospital, Southampton, SO16 6YD, UK; Clinical & Experimental Sciences, Faculty of Medicine, Southampton General Hospital, University of Southampton, Southampton, SO16 6YD, UK.
Martin FeelischNIHR Southampton Biomedical Research Center, University of Southampton, Southampton, General Hospital, Southampton, SO16 6YD, UK; Clinical & Experimental Sciences, Faculty of Medicine, Southampton General Hospital, University of Southampton, Southampton, SO16 6YD, UK. Electronic address: M.Feelisch@soton.ac.uk.
University of Notre Dame · USIndiana University South Bend · USSouthampton General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matcha and green tea catechins such as (-)-epicatechin (EC), (-)-epigallocatechin (EGC) and (-)-epigallocatechin gallate (EGCG) have long been studied for their antioxidant and health-promoting effects. Using specific fluorophores for H

Indexed as

CatechinHydrogen SulfideAntioxidantsChromatography, LiquidHEK293 CellsHumansHydrogen PeroxideSulfidesTandem Mass SpectrometryTeaThiosulfatesAntioxidantsCatechinHydrogen PeroxideHydrogen SulfidepolysulfideSulfidesTeaThiosulfatesAntioxidantsReactive oxygen speciesReactive sulfide species

Identifiers

PMID33002760
PMCPMC7527747
OpenAlexW3087544605

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.