ArticleTropical medicine and infectious disease2020
The Zika Virus Individual Participant Data Consortium: A Global Initiative to Estimate the Effects of Exposure to Zika Virus during Pregnancy on Adverse Fetal, Infant, and Child Health Outcomes.
Article in Tropical medicine and infectious disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neurodevelopmental assessments used to measure preschoolers' cognitive development in Latin America: a systematic review.Journal of pediatric psychology · 2024Pooled it
- Overlapping research efforts in a global pandemic: a rapid systematic review of COVID-19-related individual participant data meta-analyses.BMC health services research · 2023Pooled it
- Pooled it
- Improving neurodevelopment in Zika-exposed children: A randomized controlled trial.PLoS neglected tropical diseases · 2022Trial
- Comparing Adverse Health Outcomes in Infants Born to Women Monoinfected with Zika Virus or Infected with Both Zika and Chikungunya Viruses during Pregnancy: A Prospective Cohort Study in Pernambuco, Brazil (2015-2017).The American journal of tropical medicine and hygiene · 2026Article
- Article
- Identifying the motivators, benefits and barriers to sharing participant-level data and samples: results from an international online survey of acute febrile illness cohort teams.BMC medical ethics · 2026Article
- How to conduct an individual participant data meta-analysis in response to an emerging pathogen: Lessons learned from Zika and COVID-19.Research synthesis methods · 2026Review
- A Fully-Integrated Bayesian Approach for the Imputation and Analysis of Derived Outcome Variables With Missingness.Statistics in medicine · 2026Article
- Zika in Infants and Pregnancy (ZIP) study: results from a prospective international cohort study of prenatal Zika virus infection and adverse fetal and infant outcomes.BMC pregnancy and childbirth · 2025Observational
- Adverse fetal and perinatal outcomes associated with Zika virus infection during pregnancy: an individual participant data meta-analysis.EClinicalMedicine · 2025Article
- Early life exposure to SARS-CoV-2 and offspring neurodevelopment: detecting a non-linear relationship requires a complex approach.Pediatric research · 2024Article
- Harnessing the power of telemedicine to accomplish international pediatric outcome research during the COVID-19 pandemic.Journal of telemedicine and telecare · 2024Article
- "I found out about Zika virus after she was born." Women's experiences of risk communication during the Zika virus epidemic in Brazil, Colombia, and Puerto Rico.PLOS global public health · 2024Article
- Preparing for the next emerging perinatal infectious disease.Pediatric research · 2024Article
- New Insights into Zika in Infants and Children.Tropical medicine and infectious disease · 2022Article
- The legacy of ZikaPLAN: a transnational research consortium addressing Zika.Global health action · 2021Review
- Epidemic preparedness: Prenatal Zika virus screening during the next epidemic.BMJ global health · 2021Review
- An initiative of cooperation in Zika virus research: the experience of the ZIKABRA study in Brazil.BMC public health · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This commentary describes the creation of the Zika Virus Individual Participant Data Consortium, a global collaboration to address outstanding questions in Zika virus (ZIKV) epidemiology through conducting an individual participant data meta-analysis (IPD-MA). The aims of the IPD-MA are to (1) estimate the absolute and relative risks of miscarriage, fetal loss, and short- and long-term sequelae of fetal exposure; (2) identify and quantify the relative importance of different sources of heterogeneity (e.g., immune profiles, concurrent flavivirus infection) for the risk of adverse fetal, infant, and child outcomes among infants exposed to ZIKV in utero; and (3) develop and validate a prognostic model for the early identification of high-risk pregnancies and inform communication between health care providers and their patients and public health interventions (e.g., vector control strategies, antenatal care, and family planning programs). By leveraging data from a diversity of populations across the world, the IPD-MA will provide a more precise estimate of the risk of adverse ZIKV-related outcomes within clinically relevant subgroups and a quantitative assessment of the generalizability of these estimates across populations and settings. The ZIKV IPD Consortium effort is indicative of the growing recognition that data sharing is a central component of global health security and outbreak response.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.