Evidence mapPaperPMID 33008496Full record

ReviewThe Urologic clinics of North America2020

The Potential Role for Immunotherapy in Biochemically Recurrent Prostate Cancer.

Marijo Bilusic, David J Einstein, Fatima H Karzai, William L Dahut, James L Gulley, Jeanny B Aragon-Ching, Ravi A Madan

Open access · greenAbstract readReview
In one paragraph

Review in The Urologic clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marijo BilusicGenitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, 13n240b, Bethesda, MD 20892, USA.
David J EinsteinDivision of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Fatima H KarzaiGenitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, 13n240b, Bethesda, MD 20892, USA.
William L DahutGenitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, 13n240b, Bethesda, MD 20892, USA.
James L GulleyGenitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, 13n240b, Bethesda, MD 20892, USA.
Jeanny B Aragon-ChingGU Medical Oncology, Inova Schar Cancer Institute, Fairfax, VA, USA.
Ravi A MadanGenitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, 13n240b, Bethesda, MD 20892, USA. Electronic address: madanr@mail.nih.gov.
National Cancer Institute · USCenter for Cancer Research · USBeth Israel Deaconess Medical Center · US

Funding

Cancer ImmunotherapyZIABC010666 · DIVISION OF BASIC SCIENCES - NCI · 2025 to 2025
$4.8M
Intramural NIH HHS ZIA BC010666
6 · The paper itself

Abstract

Biochemically recurrent prostate cancer represents a stage of prostate cancer where conventional (continued on next page) computed tomography and technetium Tc 99m bone scan imaging are unable to detect disease after curative intervention despite rising prostate-specific antigen. There is no clear standard of care and no systemic therapy has been shown to improve survival. Immunotherapy-based treatments potentially are attractive options relative to androgen deprivation therapy due to the generally more favorable side-effect profile. Biochemically recurrent prostate cancer patients have a low tumor burden and likely lymph node-based disease, which may make them more likely to respond to immunotherapy.

Indexed as

AgedAndrogen AntagonistsCombined Modality TherapyDisease-Free SurvivalHumansImmunotherapyMaleMiddle AgedNeoplasm Recurrence, LocalPatient SelectionPrognosisProstate-Specific AntigenProstatic NeoplasmsRisk AssessmentRoleSurvival AnalysisAndrogen AntagonistsProstate-Specific AntigenBiochemically recurrentImmunotherapy-based treatmentProstate cancerSystemic therapy

Identifiers

PMID33008496
PMCPMC8177734
OpenAlexW3090718098

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.