Evidence map›Paper›PMID 33015052›Full record

ArticleFrontiers in cell and developmental biology2020

AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes.

Pei He, Zhiling Li, Feng Xu, Gaizhen Ru, Yue Huang, En Lin, Sanfeng Peng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. OiScience · 2024
    Article
  7. Article
  8. Article
  9. Linking ROS Levels to Autophagy: The Key Role of AMPK.Antioxidants (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pei HeDepartment of Reproductive Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Zhiling LiDepartment of Reproductive Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Feng XuDepartment of Respiratory Medicine, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Gaizhen RuDepartment of Reproductive Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Yue HuangDepartment of Reproductive Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
En LinDepartment of Reproductive Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Sanfeng PengDepartment of Reproductive Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
First Affiliated Hospital of Shantou University Medical College · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In zygotes, the capacity of G2/M checkpoint and DNA repair mechanisms to respond to DNA damage varies depending on different external stressors. In our previous studies, we found that mild oxidative stress induced a G2/M phase delay in mouse zygotes fertilized

Indexed as

AMPKDNA damageG2 arrestin vitro fertilized embryosoxidative stressp21p53

Identifiers

PMID33015052
PMCPMC7505953
OpenAlexW3083817165

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.