ReviewNPJ schizophrenia2020
Progression from being at-risk to psychosis: next steps.
Review in NPJ schizophrenia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Examining the variability of neurocognitive functioning in individuals at clinical high risk for psychosis: a meta-analysis.Translational psychiatry · 2022Pooled it
- Treatment Choices for Youth at Clinical High-Risk of Psychosis: Methods of an Open Trial.Early intervention in psychiatry · 2025Trial
- Trial
- Family communication and the efficacy of family focused therapy in individuals at clinical high risk for psychosis with comorbid anxiety.Early intervention in psychiatry · 2023Trial
- Association Between Social and Role Functioning and Transition to Psychosis in the North American Prodrome Longitudinal Study Consortium.Schizophrenia bulletin · 2026Article
- Brain texture alterations predict subtle visual perceptual dysfunctions in recent onset psychosis and clinical high-risk state.Translational psychiatry · 2026Article
- Effects of palmitoylethanolamide in clinical high-risk for psychosis: A nonrandomized open-label trial.Brain, behavior, & immunity - health · 2025Article
- Probabalistic reinforcement learning impairments predict negative symptom severity and risk for conversion in youth at clinical high-risk for psychosis.Psychological medicine · 2025Article
- Three-year course of clinical high-risk symptoms for psychosis in the community: a latent class analysis.Epidemiology and psychiatric sciences · 2025Article
- Exosomal microRNA signatures in youth at clinical high risk for bipolar disorder.Frontiers in psychiatry · 2025Article
- Are factors that predict conversion to psychosis associated with initial transition to a high risk state? An adolescent brain cognitive development study analysis.Schizophrenia research · 2024Article
- Kenya Psychosis-Risk Outcomes Study (KePROS): Development of an Accelerated Medicine Partnership Schizophrenia-Aligned Project in Africa.Schizophrenia bulletin open · 2024Article
- The Ethics of Risk Prediction for Psychosis and Suicide Attempt in Youth Mental Health.The Journal of pediatrics · 2023Review
- Magnetic resonance advanced imaging analysis in adolescents: cortical thickness study to identify attenuated psychosis syndrome.Neuroradiology · 2023Article
- Graph-based analysis of EEG for schizotypy classification applying flicker Ganzfeld stimulation.Schizophrenia (Heidelberg, Germany) · 2023Article
- Migrant status, clinical symptoms and functional outcome in youth at clinical high risk for psychosis: findings from the NAPLS-3 study.Social psychiatry and psychiatric epidemiology · 2023Article
- Measurement fidelity of clinical assessment methods in a global study on identifying reproducible brain signatures of obsessive-compulsive disorder.Neuropsychology · 2023Article
- Investigation of social and cognitive predictors in non-transition ultra-high-risk' individuals for psychosis using spiking neural networks.Schizophrenia (Heidelberg, Germany) · 2023Article
- Patient-Reported Outcome Measures in Clinical High Risk for Psychosis: A Systematic Review.Schizophrenia bulletin open · 2023Review
- Cognitive-Behavioral Social Skills Training: Outcome of a Randomized Controlled Trial for Youth at Risk of Psychosis.Schizophrenia bulletin open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past 20 years there has been a great deal of research into those considered to be at risk for developing psychosis. Much has been learned and studies have been encouraging. The aim of this paper is to offer an update of the current status of research on risk for psychosis, and what the next steps might be in examining the progression from CHR to psychosis. Advances have been made in accurate prediction, yet there are some methodological issues in ascertainment, diagnosis, the use of data-driven selection methods and lack of external validation. Although there have been several high-quality treatment trials the heterogeneity of this clinical high-risk population has to be addressed so that their treatment needs can be properly met. Recommendations for the future include more collaborative research programmes, and ensuring they are accessible and harmonized with respect to criteria and outcomes so that the field can continue to move forward with the development of large collaborative consortiums as well as increased funding for multisite projects.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.