Evidence map›Paper›PMID 33034761›Full record

ArticleMedical oncology (Northwood, London, England)2020

The prostate-specific membrane antigen (PSMA)-targeted radiotracer

Prasanna Santhanam, Jonathon Russell, Lisa M Rooper, Paul W Ladenson, Martin G Pomper, Steven P Rowe

Open access · greenAbstract read
In one paragraph

Article in Medical oncology (Northwood, London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. Current trends in the characterization and monitoring of vascular response to cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  5. Potential application of [EJNMMI research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prasanna SanthanamDivision of Endocrinology, Diabetes, & Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. psantha1@jhmi.edu.ORCID http://orcid.org/0000-0003-4822-2705
Jonathon RussellDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Lisa M RooperDivision of Surgical Pathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Paul W LadensonDivision of Endocrinology, Diabetes, & Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Martin G PomperDivision of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Steven P RoweDivision of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Johns Hopkins University · US

Funding

Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
Small Molecule PSMA-Targeted Alpha TherapyR01CA184228 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G, ZALUTSKY, MICHAEL ROD · 2014 to 2023
$3.6M
PSMA Directed Imaging of Prostate Cancer Focus on Androgen Receptor DynamicsU01CA183031 · NCI · JOHNS HOPKINS UNIVERSITY · PI DEWEESE, THEODORE L, POMPER, MARTIN G · 2015 to 2017
$1.2M
NCI NIH HHS R01 CA134675NCI NIH HHS R01 CA184228NCI NIH HHS U01 CA183031NIBIB NIH HHS P41 EB024495NIH HHS CA134675NIH HHS CA183031NIH HHS CA184228
6 · The paper itself

Abstract

Prostate-specific membrane antigen (PSMA; also termed glutamate carboxypeptidase II (GCP II)) is abundantly expressed in prostate cancer. It has been shown recently that PSMA is expressed in neovasculature of differentiated thyroid cancer. In this study, we show that

Indexed as

AdultAntigens, SurfaceDrug Resistance, NeoplasmFluorine RadioisotopesFluorodeoxyglucose F18Glutamate Carboxypeptidase IIHumansIodine RadioisotopesMaleMiddle AgedNeoplasm, ResidualNeovascularization, PathologicPositron Emission Tomography Computed TomographyRadiopharmaceuticalsThyroid NeoplasmsWhole Body ImagingAntigens, SurfaceFluorine RadioisotopesFluorodeoxyglucose F18FOLH1 protein, humanGlutamate Carboxypeptidase IIIodine RadioisotopesRadiopharmaceuticals18F-DCFPyLDTCPSMATumor neovasculature

Identifiers

PMID33034761
PMCPMC7759157
OpenAlexW3091971753

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.