Evidence map›Paper›PMID 33037141›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo.

Douglas F Pinheiro, Antal B Szenes-Nagy, Megan M Maurano, Melanie Lietzenmayer, Maria M Klicznik, Raimund Holly, Daniel Kirchmeier, Sophie Kitzmueller, Gertrude Achatz-Straussberger, Michael D Rosenblum and 3 more

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Douglas F PinheiroDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.
Antal B Szenes-NagyDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.ORCID 0000-0003-4623-0875
Megan M MauranoDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.ORCID 0000-0003-1013-7572
Melanie LietzenmayerDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.
Maria M KlicznikDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.ORCID 0000-0002-3871-5859
Raimund HollyDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.
Daniel KirchmeierDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.ORCID 0000-0001-7526-9360
Sophie KitzmuellerDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.
Gertrude Achatz-StraussbergerDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.ORCID 0000-0002-1817-7870
Michael D RosenblumDepartment of Dermatology, University of California, San Francisco, San Francisco, CA 94143; and.
Josef ThalhamerDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria.
Abul K AbbasDepartment of Pathology, University of California, San Francisco, San Francisco, CA 94143.
Iris K GratzDepartment of Biosciences, University of Salzburg, 5020 Salzburg, Austria; iris.gratz@sbg.ac.at.ORCID 0000-0001-7470-7277

Funding

GENERATION AND MAINTENANCE OF EFFECTOR AND REGULATORY T CELLS IN THE SKINR03AR064554 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRATZ, IRIS KARINA · 2013 to 2015
$237k
NIAMS NIH HHS R03 AR064554
6 · The paper itself

Abstract

Immune homeostasis in peripheral tissues is, to a large degree, maintained by the differentiation and action of regulatory T cells (Treg) specific for tissue Ags. Using a novel mouse model, we have studied the differentiation of naive CD4

Indexed as

Lymphocyte ActivationAnimalsAutoimmune DiseasesCell DifferentiationDisease Models, AnimalForkhead Transcription FactorsHumansMiceMice, TransgenicOvalbuminReceptors, Antigen, T-CellSignal TransductionSirolimusSkinT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsForkhead Transcription FactorsFoxp3 protein, mousemTOR protein, mouseOvalbuminReceptors, Antigen, T-CellSirolimusTOR Serine-Threonine Kinases

Identifiers

PMID33037141
PMCPMC8606034

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.