Evidence map›Paper›PMID 33040238›Full record

ReviewNeuroscience bulletin2020

Purinergic Modulation of Activity in the Developing Auditory Pathway.

Sasa Jovanovic, Ivan Milenkovic

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuroscience bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Medial Olivocochlear Efferent Modulation of Cochlear Micromechanics Requires P2X4 Receptor in Outer Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. Developmental expression of calretinin in the mouse cochlea.European journal of histochemistry : EJH · 2024
    Article
  4. Selective Vulnerability of GABAergic Inhibitory Interneurons to Bilirubin Neurotoxicity in the Neonatal Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  5. Purinergic Signalling in the Cochlea.International journal of molecular sciences · 2022
    Review
  6. Review
  7. The CleLife · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sasa JovanovicSchool of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, 26129, Oldenburg, Germany.ORCID http://orcid.org/0000-0002-5079-3948
Ivan MilenkovicSchool of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, 26129, Oldenburg, Germany. ivan.milenkovic@uol.de.ORCID http://orcid.org/0000-0003-1431-9031
Carl von Ossietzky Universität Oldenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purinergic P2 receptors, activated by endogenous ATP, are prominently expressed on neuronal and non-neuronal cells during development of the auditory periphery and central auditory neurons. In the mature cochlea, extracellular ATP contributes to ion homeostasis, and has a protective function against noise exposure. Here, we focus on the modulation of activity by extracellular ATP during early postnatal development of the lower auditory pathway. In mammals, spontaneous patterned activity is conveyed along afferent auditory pathways before the onset of acoustically evoked signal processing. During this critical developmental period, inner hair cells fire bursts of action potentials that are believed to provide a developmental code for synaptic maturation and refinement of auditory circuits, thereby establishing a precise tonotopic organization. Endogenous ATP-release triggers such patterned activity by raising the extracellular K

Indexed as

Adenosine TriphosphateAuditory PathwaysAnimalsCochleaHair Cells, Auditory, InnerReceptors, Purinergic P2XSpiral GanglionAdenosine TriphosphateReceptors, Purinergic P2XAuditory brainstemAuditory systemCochleaDevelopmentPurinergic signalingSpiral ganglion

Identifiers

PMID33040238
PMCPMC7674525
OpenAlexW3091802378

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.