Evidence map›Paper›PMID 33042111›Full record

ArticleFrontiers in immunology2020

Inhibition of Angiotensin Converting Enzyme Impairs Anti-staphylococcal Immune Function in a Preclinical Model of Implant Infection.

Rishi Trikha, Danielle Greig, Benjamin V Kelley, Zeinab Mamouei, Troy Sekimura, Nicolas Cevallos, Thomas Olson, Ameen Chaudry, Clara Magyar, Daniel Leisman and 3 more

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Exploring the Impact of ACE Inhibition in Immunity and Disease.Journal of the renin-angiotensin-aldosterone system : JRAAS · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Rishi TrikhaDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Danielle GreigDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Benjamin V KelleyDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Zeinab MamoueiDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Troy SekimuraDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Nicolas CevallosDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Thomas OlsonDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Ameen ChaudryDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Clara MagyarDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Daniel LeismanIcahn School of Medicine at Mount Sinai, New York, NY, United States.
Alexandra StavrakisDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
Michael R YeamanDivisions of Molecular Medicine and Infectious Diseases, Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA, United States.
Nicholas M BernthalDepartment of Orthopaedic Surgery, University of California, Los Angeles, CA, United States.
University of California, Los Angeles · USIcahn School of Medicine at Mount Sinai · USUCLA Medical Center · US

Funding

Modifying and Delivering Antimicrobials to Prevent Orthopaedic Implant InfectionsK08AR069112 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BERNTHAL, NICHOLAS M. · 2016 to 2019
$704k
NIAMS NIH HHS K08 AR069112
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiotensin-Converting Enzyme InhibitorsAngiotensin II Type 1 Receptor BlockersAnimalsBacterial LoadBiofilmsBone WiresDisease Models, AnimalHost-Pathogen InteractionsLisinoprilLosartanMice, Inbred C57BLPeptidyl-Dipeptidase AProsthesis-Related InfectionsRenin-Angiotensin SystemStaphylococcal InfectionsStaphylococcus aureusAngiotensin-Converting Enzyme InhibitorsAngiotensin II Type 1 Receptor BlockersLisinoprilLosartanPeptidyl-Dipeptidase Aangiotensin-converting enzyme inhibitorangiotensin II receptor blockerbioluminescenceimplantinfection

Identifiers

PMID33042111
PMCPMC7518049
OpenAlexW3084934130

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.