Evidence map›Paper›PMID 33059127›Full record

ReviewNutrition (Burbank, Los Angeles County, Calif.)2021

Obesity, malnutrition, and trace element deficiency in the coronavirus disease (COVID-19) pandemic: An overview.

Debora Fedele, Antonella De Francesco, Sergio Riso, Alessandro Collo

Open access · greenAbstract readReview
In one paragraph

Review in Nutrition (Burbank, Los Angeles County, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 5 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 5 syntheses or guidelines pooled it, 131 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Pooled it
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Copper biomarkers and their relationship with dyslipidemia in women with obesity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Observational
  18. Nutritional problems of patients with COVID-19 receiving dietetic treatment in primary care.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
    Observational
  19. Article
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Debora FedeleDietetic and Clinical Nutrition Unit, San Giovanni Battista Hospital, Città della Salute e della Scienza, Turin, Italy. Electronic address: dfedele@cittadellasalute.to.it.
Antonella De FrancescoDietetic and Clinical Nutrition Unit, San Giovanni Battista Hospital, Città della Salute e della Scienza, Turin, Italy.
Sergio RisoDietetic and Clinical Nutrition Unit, Maggiore della Carità Hospital, Novara, Italy.
Alessandro ColloDietetic and Clinical Nutrition Unit, Maggiore della Carità Hospital, Novara, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliero Universitaria San Giovanni Battista · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The world is currently facing the coronavirus disease (COVID-19) pandemic which places great pressure on health care systems and workers, often presents with severe clinical features, and sometimes requires admission into intensive care units. Derangements in nutritional status, both for obesity and malnutrition, are relevant for the clinical outcome in acute illness. Systemic inflammation, immune system impairment, sarcopenia, and preexisting associated conditions, such as respiratory, cardiovascular, and metabolic diseases related to obesity, could act as crucial factors linking nutritional status and the course and outcome of COVID-19. Nevertheless, vitamins and trace elements play an essential role in modulating immune response and inflammatory status. Overall, evaluation of the patient's nutritional status is not negligible for its implications on susceptibility, course, severity, and responsiveness to therapies, in order to perform a tailored nutritional intervention as an integral part of the treatment of patients with COVID-19. The aim of this study was to review the current data on the relevance of nutritional status, including trace elements and vitamin status, in influencing the course and outcome of the disease 3 mo after the World Health Organization's declaration of COVID-19 as a pandemic.

Indexed as

Cardiovascular DiseasesCOVID-19HumansInflammationMalnutritionNutritional StatusObesityPandemicsRespiratory Tract DiseasesSarcopeniaSARS-CoV-2Trace ElementsVirus ReplicationTrace ElementsCOVID-19Nutritional statusSarcopeniaTrace elementsVitamins

Identifiers

PMID33059127
PMCPMC7832575
OpenAlexW3084357599

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.