Evidence map›Paper›PMID 33067186›Full record

ArticleDisease models & mechanisms2020

Alcoholic hepatitis and metabolic disturbance in female mice: a more tractable model than

Lozan Sheriff, Reenam S Khan, Raquel Saborano, Richard Wilkin, Nguyet-Thin Luu, Ulrich L Gunther, Stefan G Hubscher, Philip N Newsome, Patricia F Lalor

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease models & mechanisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Tracer-Based Metabolic Analysis by NMR in Intact Perfused Human Liver Tissue.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Lozan SheriffCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0001-8364-9080
Reenam S KhanCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-4114-4567
Raquel SaboranoCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-4683-6140
Richard WilkinCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0001-5459-3962
Nguyet-Thin LuuCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-2696-4145
Ulrich L GuntherInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Stefan G HubscherCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.
Philip N NewsomeCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0001-6085-3652
Patricia F LalorCentre for Liver and Gastroenterology Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK p.f.lalor@bham.ac.uk.ORCID 0000-0001-8733-5273
National Institute for Health Research · GBUniversity of Birmingham · GB

Funding

Medical Research Council MC_PC_17169Medical Research Council MR-S001581Medical Research Council MR/S001581/1
6 · The paper itself

Abstract

Alcoholic hepatitis (AH) is the dramatic acute presentation of alcoholic liver disease, with a 15% mortality rate within 28 days in severe cases. Research into AH has been hampered by the lack of effective and reproducible murine models that can be operated under different regulatory frameworks internationally. The liquid Lieber-deCarli (LdC) diet has been used as a means of

Indexed as

AnimalsDisease Models, AnimalEthanolFatty LiverFemaleHepatitis, AlcoholicHepatocytesInflammationMice, Inbred C57BLNF-E2-Related Factor 2RegenerationEthanolNF-E2-Related Factor 2Alcoholic hepatitisFibrogenesisInflammationMurineSteatosis

Identifiers

PMID33067186
PMCPMC7790192
OpenAlexW3093277501

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.