Evidence map›Paper›PMID 33067334›Full record

GuidelineGut2021

Guidelines on the management of ascites in cirrhosis.

Guruprasad P Aithal, Naaventhan Palaniyappan, Louise China, Suvi Härmälä, Lucia Macken, Jennifer M Ryan, Emilie A Wilkes, Kevin Moore, Joanna A Leithead, Peter C Hayes and 2 more

Open access · bronzeAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Gut, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 12 pooled it
28.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 12 syntheses or guidelines pooled it, 653 citations in OpenAlex.

  1. Low-Dose vs. Standard Care Iv Human Albumin During Large-Volume Paracentesis in Patients With Liver Cirrhosis: A Systematic Review.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Guideline
  7. Guideline
  8. [Guidelines on the management of ascites in cirrhosis (2023 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Guideline
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Trial
  14. Trial
  15. Trial
  16. AI-assisted ascites volumetry for prognostic stratification in HCC treated with Atezolizumab/Bevacizumab.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Personalised Long-Term Albumin Treatment Based on Three-Month Ascites Response in Patients With Decompensated Cirrhosis.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Observational

120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Guruprasad P AithalNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK guru.aithal@nottingham.ac.uk.ORCID 0000-0003-3924-4830
Naaventhan PalaniyappanNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
Louise ChinaInstitute of Liver Disease and Digestive Health, University College London, London, UK.
Suvi HärmäläInstitute of Health Informatics, University College London, London, UK.
Lucia MackenDepartment of Clinical and Experimental Medicine, Brighton and Sussex Medical School, Brighton, UK.ORCID 0000-0003-4324-0138
Jennifer M RyanInstitute of Liver Disease and Digestive Health, University College London, London, UK.
Emilie A WilkesNottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, UK.
Kevin MooreInstitute of Liver Disease and Digestive Health, University College London, London, UK.
Joanna A LeitheadLiver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Peter C HayesHepatology Department, Royal Infirmary of Edinburgh, Edinburgh, UK.
Alastair J O'BrienInstitute of Liver Disease and Digestive Health, University College London, London, UK.ORCID 0000-0002-9168-7009
Sumita VermaDepartment of Clinical and Experimental Medicine, Brighton and Sussex Medical School, Brighton, UK.
University College London · GBNottingham University Hospitals NHS Trust · GBBrighton and Sussex Medical School · GBCambridge University Hospitals NHS Foundation Trust · GBEdinburgh Royal Infirmary · GBRoyal Free London NHS Foundation Trust · GB

Funding

Department of Health PB-PG-0214-33068
6 · The paper itself

Abstract

The British Society of Gastroenterology in collaboration with British Association for the Study of the Liver has prepared this document. The aim of this guideline is to review and summarise the evidence that guides clinical diagnosis and management of ascites in patients with cirrhosis. Substantial advances have been made in this area since the publication of the last guideline in 2007. These guidelines are based on a comprehensive literature search and comprise systematic reviews in the key areas, including the diagnostic tests, diuretic use, therapeutic paracentesis, use of albumin, transjugular intrahepatic portosystemic stent shunt, spontaneous bacterial peritonitis and beta-blockers in patients with ascites. Where recent systematic reviews and meta-analysis are available, these have been updated with additional studies. In addition, the results of prospective and retrospective studies, evidence obtained from expert committee reports and, in some instances, reports from case series have been included. Where possible, judgement has been made on the quality of information used to generate the guidelines and the specific recommendations have been made according to the 'Grading of Recommendations Assessment, Development and Evaluation (GRADE)' system. These guidelines are intended to inform practising clinicians, and it is expected that these guidelines will be revised in 3 years' time.

Indexed as

AscitesHumansLiver Cirrhosisascitescirrhosis

Identifiers

PMID33067334
PMCPMC7788190
OpenAlexW2144187699

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.