ArticleSleep & breathing = Schlaf & Atmung2021
The association between micronutrient status and sleep quality in patients with depression: a case-control study.
Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.Frontiers in endocrinology · 2024Trial
- Association between the plant-based Mediterranean diet and neuropsychological distress of the breastfeeding mothers and their infants.BMC pediatrics · 2025Article
- Specific Nutrients Mediate the Association of Food Insecurity and Sleep Regularity Index (SRI) in U.S. Adults: NHANES 2011-2014.Nutrients · 2025Article
- Prevalence of Premenstrual Syndrome and Its Association With Dietary Inflammatory Index Among Young Females: A Cross-Sectional Study.Journal of nutrition and metabolism · 2025Article
- Development and Validation of a Food Frequency Questionnaire for Evaluating the Nutritional Status of Patients with Serious Mental Illnesses (DIETQ-SMI) in Bahrain.Brain sciences · 2024Article
- From OCD Symptoms to Sleep Disorders: The Crucial Role of Vitamin B12.Neuropsychiatric disease and treatment · 2024Article
- Article
- Association of Vitamin B12 Levels with Sleep Quality, Insomnia, and Sleepiness in Adult Primary Healthcare Users in Greece.Healthcare (Basel, Switzerland) · 2023Article
- Correlation Between Sleep Electroencephalogram, Brain-Derived Neurotrophic Factor, AVPR1B Gene Polymorphism, and Suicidal Behavior in Patients with Depression.Applied biochemistry and biotechnology · 2023Article
- Diet-related inflammation increases the odds of multiple sclerosis: Results from a large population-based prevalent case-control study in Jordan.Frontiers in nutrition · 2023Article
- The independent association between vitamin B12 and insomnia in Chinese patients with type 2 diabetes mellitus: a cross-sectional study.Nutrition & diabetes · 2022Article
- Sleep Quality Is Associated with Vitamin B12 Status in Female Arab Students.International journal of environmental research and public health · 2021Article
- Diet-Related Inflammation is Associated with Major Depressive Disorder in Bahraini Adults: Results of a Case-Control Study Using the Dietary Inflammatory Index.Journal of inflammation research · 2021Article
- Role of BMI in the Relationship Between Dietary Inflammatory Index and Depression: An Intermediary Analysis.Frontiers in medicine · 2021Article
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFew previous studies estimated the association between micronutrient status and sleep quality; no previous work was done in patients with depression compared with healthy controls.
methodsUsing a case-control design, 96 patients with depression were age- and sex-matched with 96 healthy controls. Dietary assessment utilized a standardized questionnaire, and analysis focused comprehensively on 18 micronutrient items. Sleep quality was measured using the Pittsburg Sleep Quality Index (PSQI). Descriptive statistics were used to summarize findings. Logistic regression analysis was used to identify predictors of poor sleep quality.
resultsPatients with depression had a significantly lower sleep quality than controls with PSQI scores of 7.3 ± 2.7 and 5.1 ± 2.5, respectively. The prevalence of poor sleep quality in patients with depression was almost double the prevalence of poor sleep quality in the general population. The micronutrient status of vitamin B12 and Mg successfully predicted sleep quality in healthy controls. However, in patients with depression, micronutrient status failed to predict sleep quality.
conclusionsThe current research showed that sleep quality was positively associated with Mg intake, and negatively associated with vitamin B12 in healthy adults. For patients with depression in this study sample, sleep quality was not associated with micronutrient intake status. Further research is needed to determine if intake of micronutrients can improve sleep and/or depressive symptoms in patients with depression.
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