ReviewFrontiers in neurology2020
Menopause and Brain Health: Hormonal Changes Are Only Part of the Story.
Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- The acute effect of two exercise modalities on neurocognitive responses in postmenopausal women: A randomized controlled trial.Experimental physiology · 2026Trial
- Blood proteomics of menopause map to brain aging and dementia risk.Nature medicine · 2026Article
- Role of previous parity in the relationship between lifetime physical activity and later life cognition: The Rancho Bernardo study.Journal of Alzheimer's disease : JAD · 2026Article
- Menopausal Hormone Treatment as a Preventive against the Progress of Chronic Diseases in Menopausal Women.Journal of menopausal medicine · 2026Review
- Migraine and menopause as converging factors in brain vulnerability: a hypothesis-driven perspective.The journal of headache and pain · 2026Review
- Interpreting cross-sectional comparisons of menopausal status and brain outcomes.Psychological medicine · 2026Article
- Menopause-related brain fog as a midlife window in women's brain aging: toward ecologically valid measurement and digital phenotyping.Frontiers in human neuroscience · 2026Article
- Sex differences in resting state EEG spectral power are more prominent than menstrual cycle effects in healthy young adults.Frontiers in endocrinology · 2026Article
- Gender specific associations and interactions of fat quality with sleep and mental health in the elderly.Journal of health, population, and nutrition · 2025Article
- One size does not fit all: how type of menopause and hormone therapy matters for brain health.The British journal of psychiatry : the journal of mental science · 2025Review
- Investigating links between white matter hyperintensities and menopausal status using robust age-correction methods in UK Biobank.Brain communications · 2025Article
- Associations of age at menopause, bilateral oophorectomy, hysterectomy and hormone replacement therapy with glycaemia and risk of dementia: a study based on the population-based UK Biobank cohort.BMJ public health · 2025Article
- Observational
- A systematic review on the bidirectional relationship between trauma-related psychopathology and reproductive aging.Journal of mood and anxiety disorders · 2024Article
- Article
- Oxytocin and women's health in midlife.The Journal of endocrinology · 2024Review
- Cognitive Problems in Perimenopause: A Review of Recent Evidence.Current psychiatry reports · 2023Review
- Menopausal Hormone Therapy in Older Women: Examining the Current Balance of Evidence.Drugs & aging · 2023Review
- Functional near infrared spectroscopy detects cortical activation changes concurrent with memory loss in postmenopausal women with Type II Diabetes.Experimental brain research · 2023Article
- [Cognitive and psychoemotional changes in menopausal transition: The possibility of medical correction].Problemy endokrinologii · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Most studies of menopause and brain aging have focused on the role of the sex steroid hormone, estradiol, as a key mechanisms contributing to cognitive and brain aging in women. An emerging literature demonstrates that beyond endogenous estradiol levels, menopausal symptoms, particularly vasomotor symptoms (VMS), are also key determinants of menopause-related changes in cognition and brain function. Critically, that literature shows the importance of using objective techniques to identify associations of VMS with memory performance, brain structure, and brain function. While self-report measures are important patient-centered outcomes in women's health research, objective measures of VMS typically relate more strongly to indices of cognitive and brain health. Currently, it is premature to make a causal claim about VMS and memory dysfunction, but initial findings raise the possibility that women with VMS might experience an improvement in cognition with VMS treatment. More generally, these findings underscore the utility of investigating female-specific risk factors for cognitive decline.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.