Evidence map›Paper›PMID 33074152›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021

Percutaneous coronary intervention for bifurcation coronary lesions: the 15

Francesco Burzotta, Jens Flensted Lassen, Thierry Lefèvre, Adrian P Banning, Yiannis S Chatzizisis, Thomas William Johnson, Miroslaw Ferenc, Sudhir Rathore, Remo Albiero, Manuel Pan and 6 more

Open access · greenAbstract readConsensus Statement
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 4 pooled it
40.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 4 syntheses or guidelines pooled it, 225 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effect of Drug-Coated Balloon in Side Branch Protection forFrontiers in cardiovascular medicine · 2021
    Pooled it
  4. Pooled it
  5. The "Journal of interventional cardiology · 2023
    Trial
  6. Trial
  7. Article
  8. Article
  9. Clinical and procedural outcomes of ostial left anterior descending artery intervention with or without crossover to left-main.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Article
  10. Article
  11. A Stepwise Approach to Coronary Bifurcation Stenting: Enhancing Safety and Efficacy With Modified Jailed Balloon Techniques.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  12. Review
  13. PCI for Ostial Stenosis of Left Circumflex or Left Anterior Descending Artery.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Observational
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Francesco BurzottaInsitute of Cardiology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Jens Flensted Lassen
Thierry Lefèvre
Adrian P Banning
Yiannis S Chatzizisis
Thomas William Johnson
Miroslaw Ferenc
Sudhir Rathore
Remo Albiero
Manuel Pan
Olivier Darremont
David Hildick-Smith
Alaide Chieffo
Marco Zimarino
Yves Louvard
Goran Stankovic
Università Cattolica del Sacro Cuore · IT

Funding

Patient-Specific Simulations to Guide Coronary Bifurcation StentingR01HL144690 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CHATZIZISIS, IOANNIS S · 2019 to 2023
$3.9M
NHLBI NIH HHS R01 HL144690
6 · The paper itself

Abstract

The 15th European Bifurcation Club (EBC) meeting was held in Barcelona in October 2019. It facilitated a renewed consensus on coronary bifurcation lesions (CBL) and unprotected left main (LM) percutaneous interventions. Bifurcation stenting techniques continue to be refined, developed and tested. It remains evident that a provisional approach with optional side branch treatment utilising T, T and small protrusion (TAP) or culotte continues to provide flexible options for the majority of CBL patients. Debate persists regarding the optimal treatment of side branches, including assessment of clinical significance and thresholds for bail-out treatment. In more complex CBL, especially those involving the LM, adoption of dedicated two-stent techniques should be considered. Operators using such techniques have to be fully familiar with their procedural steps and should acknowledge associated limitations and challenges. When using two-stent techniques, failure to perform a final kissing inflation is regarded as a technical failure, since it may jeopardise clinical outcome. The development of novel technical tools and drug regimens deserves attention. In particular, intracoronary imaging, bifurcation simulation, drug-eluting balloon technology and tailored antiplatelet therapy have been identified as promising tools to enhance clinical outcomes. In conclusion, the evolution of a broad spectrum of bifurcation PCI components has resulted from studies extending from bench testing to randomised controlled trials. However, further advances are still needed to achieve the ambitious goal of optimising the clinical outcomes for every patient undergoing PCI on a CBL.

Indexed as

Coronary Artery DiseasePercutaneous Coronary InterventionCoronary AngiographyHumansStentsTreatment Outcome

Identifiers

PMID33074152
PMCPMC8919527
OpenAlexW3092670855

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.