Evidence map›Paper›PMID 33076403›Full record

ReviewBiomolecules2020

Interface of Phospholipase Activity, Immune Cell Function, and Atherosclerosis.

Robert M Schilke, Cassidy M R Blackburn, Temitayo T Bamgbose, Matthew D Woolard

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. [Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Robert M SchilkeDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.
Cassidy M R BlackburnDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.ORCID 0000-0002-6589-5349
Temitayo T BamgboseDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.
Matthew D WoolardDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.
Louisiana State University Health Sciences Center Shreveport · US

Funding

Macrophage- associated lipin-1 lipid synthesis regulates foam cell inflammatory responsesR01HL131844 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI WOOLARD, MATTHEW DALE · 2017 to 2020
$1.4M
NHLBI NIH HHS R01 HL131844
6 · The paper itself

Abstract

Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane fluidity, which mediates cellular function. Phospholipases and the bioactive lipids they produce are important regulators of immune cell activity, dictating both pro-inflammatory and pro-resolving activity. During atherosclerosis, pro-inflammatory and pro-resolving activities govern atherosclerosis progression and regression, respectively. This review will look at the interface of phospholipase activity, immune cell function, and atherosclerosis.

Indexed as

AtherosclerosisGTP-Binding ProteinsHumansInflammationLipidsMacrophagesMembrane FluidityPhospholipasesSignal TransductionGTP-Binding ProteinsLipidsPhospholipasesatherosclerosislipinsmacrophagesphospholipasesT cells

Identifiers

PMID33076403
PMCPMC7602611
OpenAlexW3085965016

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.