Evidence map›Paper›PMID 33080790›Full record

ArticleCells2020

ER-to-Golgi Transport in HeLa Cells Displays High Resilience to Ca

Thomas Rauter, Sandra Burgstaller, Benjamin Gottschalk, Jeta Ramadani-Muja, Helmut Bischof, Jesse C Hay, Wolfgang F Graier, Roland Malli

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. CaFaculty reviews · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Thomas RauterMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.
Sandra BurgstallerMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.
Benjamin GottschalkMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.
Jeta Ramadani-MujaMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.
Helmut BischofMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.
Jesse C HayDivision of Biological Sciences and Center for Structural and Functional Neuroscience, The University of Montana, 32 Campus Drive, HS 302A, Missoula, MT 59812-4824, USA.
Wolfgang F GraierMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.ORCID 0000-0003-1871-3298
Roland MalliMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.ORCID 0000-0001-6327-8729
Medical University of Graz · ATUniversity of Montana · US

Funding

Regulation of ER to Golgi Transport byLuminal CalciumR15GM106323 · NIGMS · UNIVERSITY OF MONTANA · PI HAY, JESSE C · 2013 to 2022
$1.3M
Austrian Science Fund FWF I 3716Austrian Science Fund FWF P 28529Austrian Science Fund FWF W 1226NIGMS NIH HHS R15 GM106323
6 · The paper itself

Abstract

One third of all human proteins are either transmembrane or soluble secretory proteins that first target the endoplasmic reticulum (ER). These proteins subsequently leave the ER and enter the Golgi apparatus via ER-Golgi intermediate vesicular structures. Live-cell imaging of cargos fused to fluorescent proteins (FPs) enables the high-resolution visualization and characterization of secretory transport processes. Here, we performed fluorescence time-lapse imaging to assess the Ca

Indexed as

Energy MetabolismStress, PhysiologicalAdenosine TriphosphateAnimalsBiological TransportCalciumCalcium SignalingDeoxyglucoseEndoplasmic ReticulumGolgi ApparatusGreen Fluorescent ProteinsHeLa CellsHomeostasisHumansRatsSingle-Cell AnalysisAdenosine TriphosphateCalciumDeoxyglucoseGreen Fluorescent Proteinscancer cell metabolismcellular calcium homeostasiscoat protein complex II (COPII) vesiclesER-to-Golgi transportfluorescent protein technologylive-cell imagingprotein transport and sortingsecretory pathwaysubcellular ATP imagingvesicle trafficking

Identifiers

PMID33080790
PMCPMC7603030
OpenAlexW3092795986

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.