Evidence map›Paper›PMID 33086891›Full record

ArticleCell transplantation

LncRNA HCG11 Inhibits Adipocyte Differentiation in Human Adipose-Derived Mesenchymal Stem Cells by Sponging miR-204-5p to Upregulate SIRT1.

Dandan Li, Yang Liu, Wei Gao, Jiakai Han, Rongrong Yuan, Mengdi Zhang, Zhenying Ge

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dandan LiDepartment of Endocrinology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, China.
Yang LiuDepartment of Endocrinology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, China.
Wei GaoDepartment of Endocrinology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, China.
Jiakai HanDepartment of Endocrinology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, China.
Rongrong YuanDepartment of Endocrinology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, China.
Mengdi ZhangDepartment of Endocrinology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, China.
Zhenying GeSchool of Basic Medical Science, Henan University, Kaifeng, Henan Province, China.ORCID 0000-0002-4058-961X
Henan University Huaihe Hospital and Huaihe Clinical Institute · CNHenan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) have been discovered to play a key role in adipogenesis, while the role of lncRNA human leukocyte antigen complex group 11 (HCG11) in adipocyte differentiation has not been studied clearly. We used human adipose-derived mesenchymal stem cells (hAdMSCs) to establish a model of cell differentiation

Indexed as

AdipocytesBlotting, WesternCell DifferentiationCell LineCell ProliferationHumansMesenchymal Stem CellsMicroRNAsReal-Time Polymerase Chain ReactionRNA, Long NoncodingSirtuin 1long noncoding RNA HCG11, humanMicroRNAsMIRN204 microRNA, humanRNA, Long NoncodingSIRT1 protein, humanSirtuin 1adipogenesisHCG11miR-204-5pobesitySIRT1

Identifiers

PMID33086891
PMCPMC7784567
OpenAlexW3093755121

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.