ArticleBMC genomics2020
Genome-wide study of pineapple (Ananas comosus L.) bHLH transcription factors indicates that cryptochrome-interacting bHLH2 (AcCIB2) participates in flowering time regulation and abiotic stress response.
Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Integrated metabolomics and transcriptomics reveal sugar metabolism associated with cold tolerance in chrysanthemum.BMC plant biology · 2026Article
- Engineering resilient roses: molecular insights into biotic and abiotic stress adaptation.Horticulture research · 2026Article
- Identification, characterization, and expression profiling of the bHLH gene family in Beta vulgaris.BMC plant biology · 2025Article
- The StbHLH47 transcription factor negatively regulates drought tolerance in potato (Solanum tuberosum L.).BMC plant biology · 2025Article
- From natural induction to artificial regulation: a review on the mechanisms and techniques of flowering in pineapple.Frontiers in plant science · 2025Review
- Transcriptome analyses reveal the flowering regulatory networks in the desert ephemeral plantFrontiers in plant science · 2025Article
- A natural mutation in the promoter of the aconitase geneHorticulture research · 2024Article
- Basic helix-loop-helix (bHLH) gene family in rye (Secale cereale L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses.BMC genomics · 2024Article
- Comparative transcriptome analysis reveals candidate genes for cold stress response and early flowering in pineapple.Scientific reports · 2023Article
- Genome-Wide Characterization ofPlants (Basel, Switzerland) · 2023Article
- VabHLH137 promotes proanthocyanidin and anthocyanin biosynthesis and enhances resistance toHorticulture research · 2023Article
- Basic Helix-Loop-Helix Transcription Factors: Regulators for Plant Growth Development and Abiotic Stress Responses.International journal of molecular sciences · 2023Review
- Genome-wide identification and expression analysis of the bHLH gene family in cauliflower (Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Integrative Analyses of Transcriptomes and Metabolomes Reveal Associated Genes and Metabolites with Flowering Regulation in Common Vetch (International journal of molecular sciences · 2022Article
- Article
- Identification and expression analysis of pineapple sugar transporters reveal their role in the development and environmental response.Frontiers in plant science · 2022Article
- Genome-wide identification and expression analysis of the bHLH transcription factor family and its response to abiotic stress in foxtail millet (Setaria italica L.).BMC genomics · 2021Article
- Genome-wide identification and expression analysis of the bHLH transcription factor family and its response to abiotic stress in sorghum [Sorghum bicolor (L.) Moench].BMC genomics · 2021Article
- Integrated Analysis of Basic Helix Loop Helix Transcription Factor Family and Targeted Terpenoids Reveals CandidateFrontiers in plant science · 2021Article
- AtCRY2 Negatively Regulates the Functions of AtANN2 and AtANN3 in Drought Tolerance by Affecting Their Subcellular Localization and Transmembrane CaFrontiers in plant science · 2021Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTranscription factors (TFs) are essential regulators of growth and development in eukaryotes. Basic-helix-loop-helix (bHLHs) is one of the most significant TFs families involved in several critical regulatory functions. Cryptochrome-interacting bHLH (CIB) and cryptochromes form an extensive regulatory network to mediate a plethora of pathways. Although bHLHs regulate critical biological processes in plants, the information about pineapple bHLHs remains unexplored.
resultsHere, we identified a total of 121 bHLH proteins in the pineapple genome. The identified genes were renamed based on the ascending order of their gene ID and classified into 18 subgroups by phylogenetic analysis. We found that bHLH genes are expressed in different organs and stages of pineapple development. Furthermore, by the ectopic expression of AcCIB2 in Arabidopsis and complementation of Atcib2 mutant, we verified the involvement of AcCIB2 in photomorphogenesis and abiotic stress response.
conclusionsOur findings revealed that AcCIB2 plays an essential role in flowering time regulation and abiotic stress response. The present study provides additional insights into the current knowledge of bHLH genes and suggests their potential role in various biological processes during pineapple development.
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