Evidence map›Paper›PMID 33098764›Full record

ArticleMolecular cell2020

Insights into Lysosomal PI(3,5)P

Joshua A Lees, PeiQi Li, Nikit Kumar, Lois S Weisman, Karin M Reinisch

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 90 citations in OpenAlex.

  1. Quantitative comparison of PI(3,5)PMolecular biology of the cell · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Quantitative comparison of PI(3,5)PbioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Review
  18. Article
  19. [Analysis ofZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  20. Development of a Second-Generation,Journal of medicinal chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joshua A LeesDepartment of Cell Biology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
PeiQi LiDepartment of Cell Biology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Nikit KumarDepartment of Cell Biology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Lois S WeismanLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Karin M ReinischDepartment of Cell Biology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. Electronic address: karin.reinisch@yale.edu.
Yale University · USUniversity of Michigan–Ann Arbor · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Molecular Basis for Membrane Lipid HomeostasisR35GM131715 · NIGMS · YALE UNIVERSITY · PI KARIN M REINISCH · 2019 to 2026
$6.5M
Phosphoinositide signaling: novel potential targets for Huntington diseaseR01NS099340 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEISMAN, LOIS S · 2017 to 2021
$2.7M
Pathophysiology of Plasma Membrane PI4P GenerationR01GM114068 · NIGMS · YALE UNIVERSITY · PI REINISCH, KARIN M · 2015 to 2018
$2.0M
NIDDK NIH HHS P30 DK020572NIGMS NIH HHS R01 GM114068NIGMS NIH HHS R35 GM131715NINDS NIH HHS R01 NS099340
6 · The paper itself

Abstract

The phosphoinositide PI(3,5)P

Indexed as

HomeostasisCell MembraneFlavoproteinsHumansIntracellular Signaling Peptides and ProteinsLysosomesMembrane ProteinsPhosphatidylinositol 3-KinasesPhosphatidylinositol PhosphatesPhosphoric Monoester HydrolasesPhosphorylationProtein BindingProtein ConformationProtein TransportFIG4 protein, humanFlavoproteinsIntracellular Signaling Peptides and ProteinsMembrane Proteinsphosphatidylinositol 3,5-diphosphatePhosphatidylinositol 3-KinasesPhosphatidylinositol PhosphatesPhosphoric Monoester HydrolasesPIKFYVE protein, humanVAC14 protein, humanlipid kinaselipid phosphatasephosphoinositide homeostasis

Identifiers

PMID33098764
PMCPMC7962480
OpenAlexW3094543672

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.