Evidence map›Paper›PMID 33100279›Full record

ArticleJournal of atherosclerosis and thrombosis2021

Outcomes of Dissection Angles as Predictor of Restenosis after Drug-Coated Balloon Treatment.

Amane Kozuki, Mitsuyoshi Takahara, Masahiro Shimizu, Yoichi Kijima, Ryoji Nagoshi, Ryudo Fujiwara, Hiroyuki Shibata, Atsushi Suzuki, Fumitaka Soga, Tomohiro Miyata and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. A Systematic Review on the Use of Intravascular Ultrasound and Optical Coherence Tomography During Femoropopliteal Endovascular Intervention.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Amane KozukiOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Mitsuyoshi TakaharaDepartment of Diabetes Care Medicine, Osaka University Graduate School of Medicine.
Masahiro ShimizuOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Yoichi KijimaOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Ryoji NagoshiOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Ryudo FujiwaraOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Hiroyuki ShibataOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Atsushi SuzukiOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Fumitaka SogaOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Tomohiro MiyataOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Yuki SakamotoOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Hidenobu SeoOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Hiroyuki AsadaOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Kouhei IsawaOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Kotaro HiguchiOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Junya ShiteOsaka Saiseikai Nakatsu Hospital, Division of Cardiology.
Saiseikai Nakatsu Hospital · JPOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe predictors of restenosis after endovascular therapy (EVT) with paclitaxel drug-coated balloons (DCBs) have not been clearly established. The present study aimed to investigate the association of post-procedural dissection, as evaluated using intravascular ultrasound (IVUS), with the risk of restenosis following femoropopliteal EVT with paclitaxel DCBs.

methodsIn the present single-center retrospective study, 60 de novo femoropopliteal lesions (44 patients) that underwent EVT with DCBs, without bail-out stenting, were enrolled. The primary outcome was 1-year primary patency. Risk factors for restenosis were evaluated using a Cox proportional hazards regression model and random survival forest analysis.

resultsThe 1-year primary patency rate was 57.2% [95% confidence interval, 45%-72%]. IVUS-evaluated post-procedural dissection was significantly associated with the risk of restenosis (P=0.002), with the best cutoff point of 64º [range, 39º-83º]. The random survival forest analysis showed that the variable importance measure of IVUS-evaluated dissection was significantly lower than that of the reference vessel diameter (P<0.001), not different from that of the lesion length (P=0.41), and significantly higher than that of any other clinical feature (all P<0.05).

conclusionIVUS-evaluated post-procedural dissection was associated with 1-year restenosis following femoropopliteal EVT with DCB.

Indexed as

Endovascular ProceduresVascular Access DevicesAgedAged, 80 and overConstriction, PathologicFemaleHumansMalePaclitaxelPeripheral Arterial DiseasePrognosisRetrospective StudiesTreatment OutcomeTubulin ModulatorsPaclitaxelTubulin ModulatorsDissectionDrug-coated balloonIntravascular ultrasoundPeripheral artery diseaseRestenosis

Identifiers

PMID33100279
PMCPMC8532059
OpenAlexW3093647201

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.