Evidence map›Paper›PMID 33100948›Full record

ArticlePrzeglad menopauzalny = Menopause review2020

Prevention and treatment of cystitis during menopause: efficacy of a nutraceutical containing D-mannose, inulin, cranberry, bearberry,

Giampaolo Mainini, Mario Passaro, Antonio Schiattarella, Pasquale De Franciscis, Mariano C Di Donna, Gennaro Trezza

Open access · goldAbstract read
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Cranberries for treating urinary tract infections.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Review
  3. Translabial ultrasound evaluation after tension-free transobturator tape technique: Outcomes based on the tape's position.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Giampaolo MaininiMenopausal Center, San Leonardo Hospital, ASL NA3 SUD, Castellammare di Stabia, Naples, Italy.
Mario PassaroASL NA3 SUD, Naples, Italy.
Antonio SchiattarellaUnit of Gynecology and Obstetrics, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Pasquale De FranciscisUnit of Gynecology and Obstetrics, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Mariano C Di DonnaDepartment of Gynecologic Oncology, Arnas Civico, University of Palermo, Palermo, Italy.
Gennaro TrezzaUnit of Gynecology and Obstetrics, Rummo Hospital, Benevento, Italy.
University of Campania "Luigi Vanvitelli" · ITAzienda Ospedaliera G.Rummo · ITIstituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim of the studyTo evaluate the efficacy of a nutraceutical compound containing Uticlin® (D-mannose, cranberry, bearberry, MATERIAL AND

methodsThis was a prospective cohort study of menopausal women recruited with a history of recurrent UTIs in the previous twelve months and who intended to treat their bladder problem without the use of antibiotics and/or anti-inflammatories. Women were proposed the use of an oral nutraceutical compound. The drug was taken for ten days, every month. Women were assigned to two parallel cohorts: patients using (group 1) or not using (group 2) this nutraceutical compound. The primary objective of the study was to evaluate the number of women with less than two infective episodes in the 6-month follow-up and less than three episodes in the 12-month follow-up. The secondary endpoints were to evaluate the reduction of related symptoms at 12-month follow-up, according to the Visual Analog Scale (VAS).

resultsAt 6 months of therapy, the reduction in the number of patients with ≥ 2 UTIs was statistically significant (

conclusionsIn menopausal women, the combination of D-mannose, inulin, cranberry, bearberry,

Indexed as

cystitisD-mannosemenopausenutraceuticalurinary tract infectionsUTIs

Identifiers

PMID33100948
PMCPMC7573332
OpenAlexW3094569723

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.