Evidence map›Paper›PMID 33102760›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2020

Prediction of outcome of treatment of acute severe ulcerative colitis using principal component analysis and artificial intelligence.

Uday C Ghoshal, Sushmita Rai, Akshay Kulkarni, Ankur Gupta

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Modern practical management of acute severe colitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  6. Article
  7. Salvage Therapy in Acute Severe Ulcerative Colitis: Current Practice and a Look to the Future.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Review
  8. Small intestinal bacterial overgrowth in patients with inflammatory bowel disease: A case-control study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Uday C GhoshalDepartment of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow India.ORCID https://orcid.org/0000-0003-0221-8495
Sushmita RaiDepartment of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow India.
Akshay KulkarniDepartment of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow India.
Ankur GuptaDepartment of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow India.ORCID https://orcid.org/0000-0001-5917-2382
Sanjay Gandhi Post Graduate Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAbout 15% patients with acute severe ulcerative colitis (UC) fail to respond to medical treatment and may require colectomy. An early prediction of response may help the treating team and the patients and their family to prepare for alternative treatment options.

methodsData of 263 patients (mean age 37.0 ± 14.0-years, 176, 77% male) with acute severe UC admitted during a 12-year period were used to study predictors of response using univariate analysis, multivariate linear principal component analysis (PCA), and nonlinear artificial neural network (ANN).

resultsOf 263 patients, 231 (87.8%) responded to the initial medical treatment that included oral prednisolone (

conclusionIt is possible to predict the response to medical treatment in patients with UC using linear and nonlinear modeling technique. Serum albumin and Hb are strong predictive factors.

Indexed as

artificial neural networkcorticosteroiddeep learningimmunosuppressantsinflammatory bowel diseasemedical treatmentoutcome predictors

Identifiers

PMID33102760
PMCPMC7578272
OpenAlexW3016413122

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.