Evidence map›Paper›PMID 33105012›Full record

ArticleEnvironmental science and pollution research international2021

NLRP3 inflammasome is involved in the mechanism of mitigative effect of selenium on lead-induced inflammatory damage in chicken kidneys.

He Huang, Jianqing Chen, Qi Sun, Yuhao Liu, You Tang, Xiaohua Teng

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

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  15. Lead (Pb) exposure and heart failure risk.Environmental science and pollution research international · 2021
    Review
  16. Article
  17. Redox Homeostasis in Poultry: Regulatory Roles of NF-κB.Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

He HuangElectrical and Information Engineering College, Jilin Agricultural Science and Technology University, Jilin, 132101, People's Republic of China.ORCID http://orcid.org/0000-0003-4442-5652
Jianqing ChenCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
Qi SunCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
Yuhao LiuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
You TangElectrical and Information Engineering College, Jilin Agricultural Science and Technology University, Jilin, 132101, People's Republic of China. tangyou9000@163.com.
Xiaohua TengCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China. tengxiaohua@neau.edu.cn.
Northeast Agricultural University · CNJilin Agricultural Science and Technology University · CN

Funding

Heilongjiang Province on Natural Fund Project of China LH2019C026National Natural Science Foundation of China 31972612
6 · The paper itself

Abstract

Lead (Pb) is a kind of widespread toxic environmental pollutant which can cause harm to organisms. Selenium (Se) has the property of mitigating Pb toxicity through decreasing oxidative stress and inflammation caused by Pb. Nucleotide-binding domain, leucine-rich-containing family, and pyrin-domain containing-3 (NLRP3) inflammasome involve in inflammation process. However, the effect of NLRP3 inflammasome in heavy metal-caused animal damage remains unknown. This research aimed to explore the mechanism of mitigative role of Se on Pb-caused renal inflammatory injury in chickens. One-week-old male chickens were provided a standard diet and drinking water, a standard diet added with 1 mg kg

Indexed as

SeleniumAnimalsChickensInflammasomesKidneyLeadMaleNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinInflammasomesLeadNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinSeleniumInflammatory injuryLead pollutionOxidative stressPoisoningRenal functionSelenium detoxification

Identifiers

PMID33105012
OpenAlexW3093694512

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.