Evidence mapPaperPMID 33109727Full record

ArticleG3 (Bethesda, Md.)2020

Regional Variation in Genetic Control of Atherosclerosis in Hyperlipidemic Mice.

Michael B Jones, Alexander An, Lisa J Shi, Weibin Shi

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael B JonesDepartments of Radiology & Medical Imaging.
Alexander AnDepartments of Radiology & Medical Imaging.
Lisa J ShiDepartments of Radiology & Medical Imaging.
Weibin ShiDepartments of Radiology & Medical Imaging, ws4v@virginia.edu.
University of Virginia · US

Funding

Genetic connections between type 2 diabetes and atherosclerosisR01DK116768 · NIDDK · UNIVERSITY OF VIRGINIA · PI WEIBIN SHI · 2022 to 2022
$399k
NHLBI NIH HHS R21 HL112281NIDDK NIH HHS R01 DK116768
6 · The paper itself

Abstract

Atherosclerosis is a polygenic disorder that often affects multiple arteries. Carotid arteries are common sites for evaluating subclinical atherosclerosis, and aortic root is the standard site for quantifying atherosclerosis in mice. We compared genetic control of atherosclerosis between the two sites in the same cohort derived from two phenotypically divergent

Indexed as

AtherosclerosisQuantitative Trait LociAnimalsFemaleGenetic Predisposition to DiseaseMaleMiceMice, Inbred C3HMice, Inbred C57BLMice, KnockoutAortaAtherosclerosisCarotid arteryGenetic lociSite Specificity

Identifiers

PMID33109727
PMCPMC7718748
OpenAlexW3096221038

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.