Evidence map›Paper›PMID 33121014›Full record

ReviewJournal of clinical medicine2020

The Oral Glucose Tolerance Test-Is It Time for a Change?-A Literature Review with an Emphasis on Pregnancy.

Delia Bogdanet, Paula O'Shea, Claire Lyons, Amir Shafat, Fidelma Dunne

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06815081 (A Study to Determine a Capillary Alternative to the Gold Standard Oral Glucose Tolerance Test), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06815081 recruitingnot on this mapstarted 2024, after this paper: background citation

A Study to Determine a Capillary Alternative to the Gold Standard Oral Glucose Tolerance Test

TypeobservationalSponsorUniversity of OxfordRan2024 to 2027Enrolled135ConditionsType 1 Diabetes (T1D), Type 2 Diabetes
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.

  1. Pooled it
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  19. Prediabetes risk classification algorithmPeerJ. Computer science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Delia BogdanetDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, Ireland.ORCID 0000-0001-6127-5049
Paula O'SheaDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, Ireland.ORCID 0000-0001-9392-1711
Claire LyonsDepartment of Clinical Biochemistry, SUHCG, University Hospital Galway, H91YR71 Galway, Ireland.
Amir ShafatDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, Ireland.ORCID 0000-0002-7966-2909
Fidelma DunneDepartment of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, Ireland.ORCID 0000-0003-3682-9403
Ollscoil na Gaillimhe – University of Galway · IEUniversity Hospital Galway · IE

Funding

Training Veterinarians for Careers in Biomedical ResearchT32OD011089 · OD · JOHNS HOPKINS UNIVERSITY · PI JOSEPH L MANKOWSKI · 2012 to 2026
$6.7M
NIH HHS T32 OD011089
6 · The paper itself

Abstract

Globally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is linked to the rise in obesity rates among women of reproductive age. GDM poses a major global health problem due to the related micro- and macro-vascular complications of subsequent Type 2 diabetes and the impact on the future health of generations through the long-term impact of GDM on both mothers and their infants. Therefore, correctly identifying subjects as having GDM is of utmost importance. The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing gestational diabetes for decades. However, this test is deeply flawed. In this review, we explore a history of the OGTT, its reproducibility and the many factors that can impact its results with an emphasis on pregnancy.

Indexed as

diabetesgestational diabetesoral glucose tolerance testreproducibility

Identifiers

PMID33121014
PMCPMC7693369
OpenAlexW3096191354

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.