Evidence map›Paper›PMID 33125946›Full record

ReviewEuropean journal of cancer (Oxford, England : 1990)2020

Repurposing anticancer drugs for the management of COVID-19.

Khalid El Bairi, Dario Trapani, Angelica Petrillo, Cécile Le Page, Hanaa Zbakh, Bruno Daniele, Rhizlane Belbaraka, Giuseppe Curigliano, Said Afqir

Open access · bronzeAbstract readReview
In one paragraph

Review in European journal of cancer (Oxford, England : 1990), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
1.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 85 citations in OpenAlex.

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  5. Adverse drug reactions associated with COVID-19 management.Naunyn-Schmiedeberg's archives of pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Khalid El BairiDepartment of Medical Oncology, Mohammed VI University Hospital, Oujda, Morocco. Electronic address: k.elbairi@ump.ac.ma.
Dario TrapaniEuropean Institute of Oncology, IRCCS, Milan, Italy.
Angelica PetrilloMedical Oncology Unit, Ospedale del Mare, Naples, Italy; University of Study of Campania "L.Vanvitelli", Naples, Italy.
Cécile Le PageResearch Institute of McGill University Health Center (RI-MUHC), Montréal, QC, Canada.
Hanaa ZbakhCenter of Marine Sciences, University of Algarve, Ed. 7, Campus of Gambelas, 8005-139, Faro, Portugal.
Bruno DanieleMedical Oncology Unit, Ospedale del Mare, Naples, Italy.
Rhizlane BelbarakaDepartment of Medical Oncology, "Bioscience et Santé" Research Laboratory, Faculty of Medicine, Cadi Ayad University, Marrakesh, Morocco.
Giuseppe CuriglianoEuropean Institute of Oncology, IRCCS, Milan, Italy; University of Milan, Department of Oncology and Hematology, Milan, Italy.
Said AfqirDepartment of Medical Oncology, Mohammed VI University Hospital, Oujda, Morocco.
Mohamed I University · MACadi Ayyad University · MAEuropean Institute of Oncology · ITMcGill University Health Centre · CAUniversity of Algarve · PTUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its outbreak in the last December, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has rapidly spread worldwide at a pandemic proportion and thus is regarded as a global public health emergency. The existing therapeutic options for COVID-19 beyond the intensive supportive care are limited, with an undefined or modest efficacy reported so far. Drug repurposing represents an enthusiastic mechanism to use approved drugs outside the scope of their original indication and accelerate the discovery of new therapeutic options. With the emergence of COVID-19, drug repurposing has been largely applied for early clinical testing. In this review, we discuss some repurposed anticancer drugs for the treatment of COVID-19, which are under investigation in clinical trials or proposed for the clinical testing.

Indexed as

COVID-19 Drug TreatmentDrug RepositioningAntineoplastic AgentsAntiviral AgentsCOVID-19HumansPandemicsSARS-CoV-2Antineoplastic AgentsAntiviral AgentsAnticancer drugsCOVID-19RepurposingSARS-CoV-2

Identifiers

PMID33125946
PMCPMC7508523
OpenAlexW3087594404

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.