Evidence map›Paper›PMID 33135395›Full record

ReviewJournal of cellular and molecular medicine2020

Anti-inflammatory and immune-modulatory impacts of berberine on activation of autoreactive T cells in autoimmune inflammation.

Seyed-Morteza Ehteshamfar, Masoume Akhbari, Jalil Tavakol Afshari, Motahareh Seyedi, Banafsheh Nikfar, Abbas Shapouri-Moghaddam, Erfan Ghanbarzadeh, Amir Abbas Momtazi-Borojeni

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 125 citations in OpenAlex.

  1. Review
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  10. Frontiers in veterinary science · 2026
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  14. Gut Microbiota-Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Seyed-Morteza EhteshamfarDepartment of Immunology, Faculty of Medicine, BuAli Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Masoume AkhbariDepartment of Molecular Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Jalil Tavakol AfshariDepartment of Immunology, Faculty of Medicine, BuAli Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Motahareh SeyediDepartment of Biology, Faculty of Science, Yazd University, Yazd, Iran.
Banafsheh NikfarPars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-6164-019X
Abbas Shapouri-MoghaddamDepartment of Immunology, Faculty of Medicine, BuAli Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Erfan GhanbarzadehSchool of Medicine, Gilan University of Medical Sciences, Gilan, Iran.
Amir Abbas Momtazi-BorojeniDepartment of Medical Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID 0000-0002-4376-1083
Mashhad University of Medical Sciences · IRGuilan University of Medical Sciences · IRIran University of Medical Sciences · IRQazvin University of Medical Sciences · IRYazd University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoreactive inflammatory CD4

Indexed as

AnimalsAnti-Inflammatory AgentsAutoimmune DiseasesAutoimmune Diseases of the Nervous SystemAutoimmunityBerberineCytokinesDemyelinating Autoimmune Diseases, CNSDendritic CellsHumansImmunologic FactorsImmunomodulationInflammationLymphocyte ActivationMacrophagesT-LymphocytesAnti-Inflammatory AgentsBerberineCytokinesImmunologic Factorsautoimmunityberberinedendritic cellinflammationmacrophageT helper cell

Identifiers

PMID33135395
PMCPMC7754052
OpenAlexW3096523997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.