Evidence map›Paper›PMID 33144846›Full record

ArticleMediators of inflammation2020

Characterization of Synovial Cytokine Patterns in Bucket-Handle and Posterior Horn Meniscal Tears.

Marco Turati, Davide Maggioni, Nicolò Zanchi, Marta Gandolla, Massimo Gorla, Paola Sacerdote, Silvia Franchi, Laura Rizzi, Alessandra Pedrocchi, Robert J Omeljaniuk and 3 more

Abstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marco TuratiOrthopedic Department, San Gerardo Hospital, Monza, Italy.ORCID https://orcid.org/0000-0002-5208-3077
Davide MaggioniSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Nicolò ZanchiSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Marta GandollaPolitecnico di Milano, NearLab, Department of Electronics, Information and Bioengineering, Milan, Italy.
Massimo GorlaOrthopedic Department, San Gerardo Hospital, Monza, Italy.
Paola SacerdoteDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Silvia FranchiDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Laura RizziSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Alessandra PedrocchiPolitecnico di Milano, NearLab, Department of Electronics, Information and Bioengineering, Milan, Italy.
Robert J OmeljaniukDepartment of Biology, Lakehead University, Thunder Bay, ON, Canada P7B5E1.
Giovanni ZattiOrthopedic Department, San Gerardo Hospital, Monza, Italy.
Antonio TorselloSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Marco BigoniOrthopedic Department, San Gerardo Hospital, Monza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specific etiology of meniscal tears, including the mechanism of lesion, location, and orientation, is considered for its contribution to subsequent joint cytokine responsiveness, healing outcomes, and by extension, appropriate lesion-specific surgical remediation. Meniscal repair is desirable to reduce the probability of development of posttraumatic osteoarthritis (PTOA) which is strongly influenced by the coordinate generation of pro- and anti-inflammatory cytokines by the injured cartilage. We now present biochemical data on variation in cytokine levels arising from two particular meniscal tears: bucket-handle (BH) and posterior horn (PH) isolated meniscal tears. We selected these two groups due to the different clinical presentations. We measured the concentrations of TNF-

Indexed as

AdolescentAdultAgedFemaleHumansInterleukin-10Interleukin-8Knee InjuriesMaleMiddle AgedSynovial FluidTibial Meniscus InjuriesTumor Necrosis Factor-alphaYoung AdultInterleukin-10Interleukin-8Tumor Necrosis Factor-alpha

Identifiers

PMID33144846
PMCPMC7599409

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.