Evidence map›Paper›PMID 33145993›Full record

ArticleMaternal & child nutrition2021

Associations of breastfeeding or formula feeding with infant anthropometry and body composition at 6 months.

Muna J Tahir, Keisuke Ejima, Peng Li, Ellen W Demerath, David B Allison, David A Fields

Abstract read
In one paragraph

Article in Maternal & child nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
  10. Article
  11. Article
  12. Infant Young Child Feeding Practices in an Indian Maternal-Child Birth Cohort in Belagavi, Karnataka.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muna J TahirDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-9611-2506
Keisuke EjimaDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.ORCID 0000-0002-1185-3987
Peng LiDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ellen W DemerathDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
David B AllisonDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.ORCID 0000-0003-3566-9399
David A FieldsDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.ORCID 0000-0002-6845-1196

Funding

Cardiovascular Disease Epidemiology &Prevention TrngT32HL007779 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PAMELA L. Lutsey, JAMES S PANKOW · 1994 to 2026
$9.3M
Maternal Obesity, Milk Composition, and Infant GrowthR01HD080444 · NICHD · UNIVERSITY OF MINNESOTA · PI ELLEN W. DEMERATH, DAVID A FIELDS · 2014 to 2026
$6.4M
Strengthening Causal Inference in Behavioral Obesity ResearchR25HL124208 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLISON, DAVID B, BROWN, ANDREW W · 2014 to 2023
$1.8M
NHLBI NIH HHS R25 HL124208NHLBI NIH HHS T32 HL007779NICHD NIH HHS R01 HD080444
6 · The paper itself

Abstract

The objective of this study was to investigate the associations of mode of feeding with infant anthropometric and body composition variables at 6 months of age. We studied 259 infants whose exclusive mode of feeding (breast or formula) to 1 month was confirmed. Standard anthropometric characteristics of the infants (weight, length and weight-for-length z scores) were obtained, and body composition (total fat mass, fat-free mass, trunk fat mass and body fat percent) was measured using dual-energy X-ray absorptiometry (DXA) at 6 months (±12 days). General linear models were used to test the associations of mode of feeding with infant anthropometric and body composition variables at 6 months after adjustment for maternal and infant covariates. In this cohort of predominantly breastfed, White infants of highly educated mothers, fat-free mass was lower (P = .002), and trunk fat mass (P = .032) and body fat percent (P < .001) were greater in breastfed infants than in formula-fed infants at 6 months of age. After adjustment for covariates, total fat-free mass was significantly lower (β = -372 g, [SE = 125, P = .003]), and body fat percent was significantly greater (β = 3.30, [SE = 0.91, P < .001]) in breastfed infants than in formula-fed infants. No other significant associations were observed. These findings support those of previous studies reporting greater fat-free mass in formula-fed infants during the first 6 months of life. Additional research is warranted to explore whether differences in infant body composition by mode of feeding persist throughout the life course and to assess causality.

Indexed as

Body CompositionBreast FeedingAnthropometryFemaleHumansInfantInfant FormulaInfant Nutritional Physiological Phenomenaanthropometrybody compositionbreastfeedingchildhood obesityearly growthinfant formula

Identifiers

PMID33145993
PMCPMC7988875

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.