ArticleThe Malaysian journal of medical sciences : MJMS2020
Evaluation of Better Staining Method among Hematoxylin and Eosin, Giemsa and Periodic Acid Schiff-Alcian Blue for the Detection of Helicobacter pylori in Gastric Biopsies.
Article in The Malaysian journal of medical sciences : MJMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 21 citations in OpenAlex.
- Helicobacter pylori CagA+ strains modulate colorectal pathology by regulating intestinal flora.BMC gastroenterology · 2025Article
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- Assessing the diagnostic accuracy of routine hematoxylin and eosin, Alcian Blue/Periodic Acid-Schiff, and Giemsa stains in the detection ofF1000Research · 2025Article
- Antibiotic Resistance and Therapeutic Efficacy ofAntibiotics (Basel, Switzerland) · 2023Article
- Article
- A Retrospective Experience ofLife (Basel, Switzerland) · 2021Article
- [Diagnostic Methods for the Detection ofActa gastroenterologica LatinoamericanaArticle
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1 author at 1 institution in 1 country.
Funding
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Abstract
backgroundThis study was undertaken to evaluate the preferred method (Giemsa or periodic acid Schiff-Alcian blue [PAS-AB] stains) of detecting
methodsThe formalin-fixed paraffin-embedded blocks of 49 gastric biopsies from different patients were collected from the archive of anatomical pathology at King Abdulaziz Medical City, National Guard, Riyadh, Saudi Arabia. From each block, three slides were prepared and analysed using the hematoxylin and eosin (H&E), Giemsa and PAS-AB stains to detect the presence/absence of
resultsThe majority of the biopsies in this study showed antrum-type gastric mucosa. Only 15 biopsies showed active gastritis, whereas the rest showed chronic gastritis. Three biopsies showed intestinal metaplasia. All were detected by PAS-AB stain, but only two-thirds were detected by H&E stain. Fifteen gastric biopsies showed
conclusionGiemsa stain has better sensitivity and specificity in gastric
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