Evidence map›Paper›PMID 33158241›Full record

SynthesisNutrients2020

Multinutrients for the Treatment of Psychiatric Symptoms in Clinical Samples: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Jeanette M Johnstone, Andrew Hughes, Joshua Z Goldenberg, Amy R Romijn, Julia J Rucklidge

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Annual Research Review: Micronutrients and their role in the treatment of paediatric mental illness.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Attention-deficit/hyperactivity disorder.Nature reviews. Disease primers · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Jeanette M JohnstoneHelfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.
Andrew HughesAdult Psychiatry, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0003-3720-2610
Joshua Z GoldenbergHelfgott Research Institute, National University of Natural Medicine, Portland, OR 97201, USA.
Amy R RomijnDepartment of Psychology, Swansea University, Swansea SA2 8PP, UK.ORCID 0000-0001-5014-1539
Julia J RucklidgeSchool of Psychology, Speech and Hearing, University of Canterbury, Christchurch 8140, New Zealand.ORCID 0000-0003-3793-7342
National University of Natural Medicine · USOregon Health & Science University · USSwansea University · GBUniversity of Canterbury · NZUniversity of Technology Sydney · AU

Funding

CAM Research Training in Neuroscience &StressT32AT002688 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI OKEN, BARRY S, SOUMYANATH, AMALA · 2005 to 2025
$7.2M
NCCIH NIH HHS 5R90AT00892403NCCIH NIH HHS T32 AT002688
6 · The paper itself

Abstract

This systematic review and meta-analysis focused on randomized controlled trials (RCT) of multinutrients consisting of at least four vitamins and/or minerals as interventions for participants with psychiatric symptoms. A systematic search identified 16 RCTs that fit the inclusion criteria (

Indexed as

NutrientsRandomized Controlled Trials as TopicHumansMental DisordersMineralsRecommended Dietary AllowancesSocial BehaviorVitaminsMineralsNutrientsVitaminsADHDautismdepressionmeta-analysismineralsmoodmultinutrientspsychiatric symptomssystematic reviewvitamins

Identifiers

PMID33158241
PMCPMC7694278
OpenAlexW3096858174

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.