Evidence map›Paper›PMID 33158246›Full record

ArticleInternational journal of molecular sciences2020

Umbilical Cord-Derived CD362

Hector Gonzalez, Colm Keane, Claire H Masterson, Shahd Horie, Stephen J Elliman, Brendan D Higgins, Michael Scully, John G Laffey, Daniel O'Toole

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. The efficacy of mesenchymal stem cell treatment and colistin-fosfomycin combination on colistin-resistant Acinetobacter baumannii sepsis model.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hector GonzalezAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
Colm KeaneAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
Claire H MastersonAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
Shahd HorieAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
Stephen J EllimanOrbsen Therapeutics Ltd., Galway H91 DET7, Ireland.
Brendan D HigginsPhysiology, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
Michael ScullyAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
John G LaffeyAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.ORCID 0000-0002-1246-9573
Daniel O'TooleAnaesthesia, School of Medicine, National University of Ireland, Galway H91 TK33, Ireland.
Ollscoil na Gaillimhe – University of Galway · IEOrbsen Therapeutics (Ireland) · IE

Funding

Health Research Board HRA-POR-2015-1099Health Research Board ILP-POR-2017-024Science Foundation Ireland 16/FRL/3845
6 · The paper itself

Abstract

Mesenchymal stromal cells (MSCs) have a multimodal, immunomodulatory mechanism of action and are now in clinical trials for single organ and systemic sepsis. However, a number of practicalities around source, homogeneity and therapeutic window remain to be determined. Here, we utilised conditioned medium from CD362

Indexed as

AnimalsAntigens, CDCecumCells, CulturedCoinfectionCord Blood Stem Cell TransplantationDisease Models, AnimalHumansLigationMaleMesenchymal Stem CellsMesenchymal Stem Cell TransplantationPuncturesRatsRats, Sprague-DawleySepsisAntigens, CDinflammationmesenchymal stem cellsepsis

Identifiers

PMID33158246
PMCPMC7672591
OpenAlexW3095744301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.