ArticlePloS one2020
Impact of diabetes mellitus on postoperative outcomes in individuals with non-small-cell lung cancer: A retrospective cohort study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025).Journal of evidence-based medicine · 2026Guideline
- Glycosylated haemoglobin and prognosis in 10,536 people with cancer and pre-existing diabetes: a meta-analysis with dose-response analysis.BMC cancer · 2022Pooled it
- Diabetes mellitus is associated with short-term postoperative outcomes in patients undergoing vats lobectomy for lung cancer: a 7-year retrospective analysis.Journal of thoracic disease · 2026Article
- Management of wound dehiscence with negative pressure in diabetic patients undergoing pulmonary resection for lung cancer.Frontiers in surgery · 2026Article
- Impact of diabetes and glycemic control during cancer care on mortality in non-metastatic solid and hematologic malignancies.Annals of medicine · 2025Article
- Postoperative outcomes in patients with diabetes after enhanced recovery thoracoscopic lobectomy.Surgical endoscopy · 2024Article
- Incidence and risk factors of pulmonary complications after lung cancer surgery: A systematic review and meta-analysis.Heliyon · 2024Article
- Is a high preoperative HbA1c level a risk factor for postoperative complications in patients with non-small-cell lung cancer?Journal of cardiothoracic surgery · 2024Article
- Association of body mass index and blood pressure variability with 10-year mortality and renal disease progression in type 2 diabetes.Acta diabetologica · 2024Article
- Multi-Modal Prehabilitation in Thoracic Surgery: From Basic Concepts to Practical Modalities.Journal of clinical medicine · 2024Review
- Prediction of postoperative pulmonary complications in older patients undergoing lobectomy for lung cancer based on skeletal muscle mass.Journal of thoracic disease · 2023Article
- The Value of Glycemic Control Prior to Cancer Diagnosis on All-Cause Mortality among Patients with Type 2 Diabetes in Dutch Primary Care.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Multiple factors affecting perioperative antibiotherapy in minimally invasive lung surgery: a retrospective case-control study.Journal of thoracic disease · 2022Article
- A retrospective study for prognostic significance of type II diabetes mellitus and hemoglobin A1c levels in non-small cell lung cancer patients treated with pembrolizumab.Translational lung cancer research · 2022Article
- The Survival Benefit for Optimal Glycemic Control in Advanced Non-Small Cell Lung Cancer Patients With Preexisting Diabetes Mellitus.Frontiers in oncology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesStudies showing that individuals with non-small cell lung cancer (NSCLC) and diabetes mellitus (DM) have reported poor outcomes after pulmonary resection with varying results. Therefore, we investigated the clinical impact of preoperative DM on postoperative morbidity and survival in individuals with resectable NSCLC. PATIENTS AND
methodsData of individuals who underwent pulmonary resection for NSCLC from 2000 to 2015 were extracted from the database of Kyoto University Hospital. The primary endpoint was the incidence of postoperative complications, and secondary endpoints were postoperative length of hospital stay and overall survival. The survival rate was analyzed using the Kaplan-Meier method.
resultsA total of 2,219 patients were eligible for the study. The median age of participants was 67 years. Among them, 39.5% were women, and 259 (11.7%) presented with DM. The effect of DM on the incidence of postoperative complications and postoperative length of hospital stay was not significant. Although the 5-year survival rates were similar in both patients with and without DM (80.2% versus 79.4%; p = 0.158), those with DM who had a hemoglobin A1c level ≥ 8.0% had the worst survival.
conclusionsIn individuals with resectable NSCLC, preoperative DM does not influence the acute phase postoperative recovery. However, poorly controlled preoperative DM could lead to low postoperative survival rates.
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