Evidence map›Paper›PMID 33171589›Full record

Trial reportNutrients2020

The Effect of Supplementation with Low Doses of a Cod Protein Hydrolysate on Satiety Hormones and Inflammatory Biomarkers in Adults with Metabolic Syndrome: A Randomized, Double-Blind Study.

Caroline Jensen, Hanna Fjeldheim Dale, Trygve Hausken, Jan Gunnar Hatlebakk, Ingeborg Brønstad, Gülen Arslan Lied, Dag Arne Lihaug Hoff

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03807752 (The Effect of Supplementation With a Marine Protein Hydrolysate in Patients With Metabolic Syndrome), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03807752 nacompletednot on this map

The Effect of Supplementation With a Marine Protein Hydrolysate in Patients With Metabolic Syndrome

TypeinterventionalSponsorHelse Møre og Romsdal HFRan2019 to 2020Enrolled33ConditionsMetabolic SyndromeArmsMPH_active, MPH_placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Caroline JensenCentre for Nutrition, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0003-2714-711X
Hanna Fjeldheim DaleCentre for Nutrition, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0002-0710-6057
Trygve HauskenCentre for Nutrition, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0001-7080-8396
Jan Gunnar HatlebakkCentre for Nutrition, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.
Ingeborg BrønstadDivision of Gastroenterology, Department of Medicine, Haukeland University Hospital, 5021 Bergen, Norway.
Gülen Arslan LiedCentre for Nutrition, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.
Dag Arne Lihaug HoffDivision of Gastroenterology, Department of Medicine, Ålesund Hospital, Møre and Romsdal Hospital Trust, 6026 Ålesund, Norway.ORCID 0000-0002-7861-2125
Haukeland University Hospital · NONorwegian University of Science and Technology · NOUniversity of Bergen · NO

Funding

Norges Forskningsråd 256684
6 · The paper itself

Abstract

Metabolic syndrome (MetS) is characterised by metabolic abnormalities that increase the risk of developing type 2 diabetes mellitus and cardiovascular disease. Altered levels of circulating ghrelin, several adipokines and inflammatory markers secreted from adipose tissue, such as leptin, adiponectin, tumor necrosis factor alpha, are observed in overweight and obese individuals. We assessed the effect of supplementation with low doses of a cod protein hydrolysate (CPH) on fasting and postprandial levels of acylated ghrelin, as well as fasting levels of adiponectin, leptin and inflammatory markers in subjects with MetS. A multicentre, double-blinded, randomized controlled trial with a parallel group design was conducted. Subjects received a daily supplement of CPH (4 g protein,

Indexed as

Dietary SupplementsAdiponectinAdultBiomarkersFemaleFish ProteinsGhrelinHumansInflammationLeptinMaleMetabolic SyndromeMiddle AgedProtein HydrolysatesSatiationAdiponectinBiomarkersFish ProteinsGhrelinLeptinProtein Hydrolysatescod protein hydrolysateinflammatory markersmetabolic syndromesatiety hormones

Identifiers

PMID33171589
PMCPMC7695186
OpenAlexW3096583522

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.