Evidence map›Paper›PMID 33174162›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2021

Renal microvascular oxygen tension during hyperoxia and acute hemodilution assessed by phosphorescence quenching and excitation with blue and red light.

Kyle Chin, Melina P Cazorla-Bak, Elaine Liu, Linda Nghiem, Yanling Zhang, Julie Yu, David F Wilson, Sergei A Vinogradov, Richard E Gilbert, Kim A Connelly and 4 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Kyle Chin *Department of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada.
Melina P Cazorla-Bak *Department of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada.
Elaine LiuDepartment of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada.
Linda NghiemKeenan Research Centre for Biomedical Science in the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Yanling ZhangKeenan Research Centre for Biomedical Science in the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Julie YuDeaprtment of Anesthesia and Perioperative Medicine, Western University, London, ON, Canada.
David F WilsonDepartment of Biochemistry and Biophysics, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Sergei A VinogradovDepartment of Biochemistry and Biophysics, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Richard E GilbertKeenan Research Centre for Biomedical Science in the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Kim A ConnellyDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Roger G EvansCardiovascular Disease Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Australia.
Andrew J BakerDepartment of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada.
C David MazerDepartment of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada.
Gregory M T HareDepartment of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. greg.hare@unityhealth.to.
St. Michael's Hospital · CAUniversity of Toronto · CAUniversity of Pennsylvania · USMonash University · AUWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe kidney plays a central physiologic role as an oxygen sensor. Nevertheless, the direct mechanism by which this occurs is incompletely understood. We measured renal microvascular partial pressure of oxygen (P

methodsWe utilized two-wavelength excitation (red and blue spectrum) of the intravascular phosphorescent oxygen sensitive probe Oxyphor PdG4 to measure renal tissue PO

resultsP

conclusionThe observed linear relationship between C

Indexed as

HemodilutionHyperoxiaAnimalsKidneyOxygenOxygen ConsumptionRatsOxygenanemiaCaO2microvascular PO2renal oxygen sensing

Identifiers

PMID33174162
OpenAlexW3102836303

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.