Evidence map›Paper›PMID 33177160›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Screening of a Panel of Low Molecular Weight Compounds That Inhibit Synovial Fibroblast Invasion in Rheumatoid Arthritis.

Tomoko Sugiura, Hiroki Kamino, Yuko Nariai, Yohko Murakawa, Masahiro Kondo, Makoto Kawakami, Noboru Ikeda, Yuji Uchio, Takeshi Urano

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tomoko SugiuraDepartment of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan; sugiura-q@hi.enjoy.ne.jp.
Hiroki KaminoDepartment of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan.ORCID 0000-0002-2489-0453
Yuko NariaiDepartment of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan.
Yohko MurakawaDepartment of Rheumatology, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan.
Masahiro KondoDepartment of Rheumatology, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan.ORCID 0000-0002-2274-7872
Makoto KawakamiJapan Community Health Care Organization Tamatsukuri Hospital, Matsue, Shimane 699-0293, Japan; and.ORCID 0000-0003-0639-0882
Noboru IkedaJapan Community Health Care Organization Tamatsukuri Hospital, Matsue, Shimane 699-0293, Japan; and.ORCID 0000-0002-3335-5217
Yuji UchioDepartment of Orthopedic Surgery, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan.
Takeshi UranoDepartment of Biochemistry, Shimane University Faculty of Medicine, Izumo, Shimane 693-8501, Japan.
Shimane University · JPMatsudo City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased invasion of synovial fibroblasts and their involvement in cartilage damage are characteristic phenotypes of rheumatoid arthritis (RA). To identify low molecular weight compounds that suppress synovial fibroblast invasion, a panel of inhibitors (

Indexed as

Anti-Inflammatory AgentsAgedArthritis, RheumatoidCell MovementDrug Evaluation, PreclinicalFemaleFibroblastsHumansMaleMiddle AgedSynovial MembraneAnti-Inflammatory Agents

Identifiers

PMID33177160
PMCPMC7718771
OpenAlexW3103595064

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.