Evidence map›Paper›PMID 33183069›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2021

Pulmonary gene delivery-Realities and possibilities.

Uday K Baliga, David A Dean

Abstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Advances in the Association Between theCurrent issues in molecular biology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Review
  8. Article
  9. Genetic Delivery and Gene Therapy in Pulmonary Hypertension.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Uday K BaligaDepartment of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA.ORCID 0000-0002-4557-8645
David A DeanDepartment of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA.ORCID 0000-0001-7748-8073

Funding

Development of a gene therapy approach to treat acute lung injury using a preclinical, large animal modelR01HL131143 · NHLBI · UNIVERSITY OF ROCHESTER · PI DEAN, DAVID A · 2016 to 2019
$3.0M
A multimodal delivery and treatment approach for Acute Lung InjuryR01HL148825 · NHLBI · UNIVERSITY OF ROCHESTER · PI DEAN, DAVID A · 2020 to 2023
$2.3M
Novel Peptide/siRNA Nanoparticles for Treatment of Acute Lung InjuryR01HL138538 · NHLBI · UNIVERSITY OF ROCHESTER · PI DEAN, DAVID A, NILSSON, BRADLEY L. · 2017 to 2020
$2.2M
Cell-specific gene delivery methods for expression and silencing in the lungR01HL120521 · NHLBI · UNIVERSITY OF ROCHESTER · PI DEAN, DAVID A · 2014 to 2017
$1.5M
NHLBI NIH HHS R01 HL120521NHLBI NIH HHS R01 HL131143NHLBI NIH HHS R01 HL138538NHLBI NIH HHS R01 HL148825
6 · The paper itself

Abstract

Delivery of genetic material to tissues

Indexed as

Gene Transfer TechniquesElectroporationExosomesExtracellular VesiclesGenetic TherapyHumansLiposomesLungLung DiseasesNanoparticlesVirusesLiposomeselectroporationexosomesgene deliveryliposomesLungnanoparticlesviral vectors

Identifiers

PMID33183069
PMCPMC7876645

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.