SynthesisBMC medicine2020
Ending malnutrition in all its forms requires scaling up proven nutrition interventions and much more: a 129-country analysis.
Synthesis in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 5 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Childhood undernutrition in North Africa: systematic review and meta-analysis of observational studies.Global health action · 2023Pooled it
- Interventions to improve the nutritional status of children under 5 years in Ethiopia: a systematic review.Public health nutrition · 2023Pooled it
- A systematic review and meta-analysis of the prevalence of childhood undernutrition in North Africa.PloS one · 2023Pooled it
- Economic Evaluations of Child Nutrition Interventions in Low- and Middle-Income Countries: Systematic Review and Quality Appraisal.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Nutrition-sensitive agriculture programs increase dietary diversity in children under 5 years: A review and meta-analysis.Journal of global health · 2022Pooled it
- Feasibility of caregiver-administered anthropometric measurements of children under age 5: evidence from Zambia.Population health metrics · 2024Trial
- Child stunting concurrent with wasting or being overweight: A 6-y follow up of a randomized maternal education trial in Uganda.Nutrition (Burbank, Los Angeles County, Calif.) · 2021Trial
- Longitudinal assessments of child growth: A six-year follow-up of a cluster-randomized maternal education trial.Clinical nutrition (Edinburgh, Scotland) · 2021Trial
- Costs and benefits of replacing preventive antenatal iron and folic acid with multiple micronutrients in 25 low- and middle-income countries.BMJ global health · 2026Article
- Scaling up evidence-based interventions to reduce maternal and child undernutrition in 125 countries: a cost-benefit analysis.International journal for equity in health · 2026Article
- Abdominal obesity in India: sex stratified multilevel estimates across 707 districts from a nationally representative cross-sectional survey.Scientific reports · 2026Article
- Exploring methods for assessing stakeholder perspectives in Scaling-Up Nutrition (SUN) countries: a scoping review.BMJ open · 2025Article
- Digital tools and technologies used in food fortification: A scoping review.Annals of the New York Academy of Sciences · 2025Article
- A case for subnational nutrition financing: The development and use of county-level investment cases in Kenya.PLOS global public health · 2025Article
- Most vulnerable diet and health profiles: identifying countries at risk through a three-theme clustering.Frontiers in public health · 2025Article
- Study on the 1990-2021 trend of global childhood respiratory infection and tuberculosis disease burden and related risk factors.Frontiers in public health · 2025Article
- Trends and cross-country inequality in the global burden of nutritional deficiencies in children, with projections to 2035: results from the Global Burden of Disease study 2021.Frontiers in nutrition · 2025Article
- Article
- The cost-effectiveness of interventions used for the screening, diagnosis and management of anaemia in pregnancy: A systematic review.PLOS global public health · 2025Article
- The cost of inaction: a global tool to inform nutrition policy and investment decisions on global nutrition targets.Health policy and planning · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSustainable Development Goal (SDG) 2.2 calls for an end to all forms of malnutrition, with 2025 targets of a 40% reduction in stunting (relative to 2012), for wasting to occur in less than 5% of children, and for a 50% reduction in anaemia in women (15-49 years). We assessed the likelihood of countries reaching these targets by scaling up proven interventions and identified priority interventions, based on cost-effectiveness.
methodsFor 129 countries, the Optima Nutrition model was used to compare 2019-2030 nutrition outcomes between a status quo (maintained intervention coverage) scenario and a scenario where outcome-specific interventions were scaled up to 95% coverage over 5 years. The average cost-effectiveness of each intervention was calculated as it was added to an expanding package of interventions.
resultsOf the 129 countries modelled, 46 (36%), 66 (51%) and 0 (0%) were on track to achieve the stunting, wasting and anaemia targets respectively. Scaling up 18 nutrition interventions increased the number of countries reaching the SDG 2.2 targets to 50 (39%), 83 (64%) and 7 (5%) respectively. Intermittent preventative treatment of malaria during pregnancy (IPTp), infant and young child feeding education, vitamin A supplementation and lipid-based nutrition supplements for children produced 88% of the total impact on stunting, with average costs per case averted of US$103, US$267, US$556 and US$1795 when interventions were consecutively scaled up, respectively. Vitamin A supplementation and cash transfers produced 100% of the total global impact on prevention of wasting, with average costs per case averted of US$1989 and US$19,427, respectively. IPTp, iron and folic acid supplementation for non-pregnant women, and multiple micronutrient supplementation for pregnant women produced 85% of the total impact on anaemia prevalence, with average costs per case averted of US$9, US$35 and US$47, respectively.
conclusionsPrioritising nutrition investment to the most cost-effective interventions within the country context can maximise the impact of funding. A greater focus on complementing nutrition-specific interventions with nutrition-sensitive ones that address the social determinants of health is critical to reach the SDG targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.