Evidence map›Paper›PMID 33187049›Full record

ReviewMolecules (Basel, Switzerland)2020

Important Flavonoids and Their Role as a Therapeutic Agent.

Asad Ullah, Sidra Munir, Syed Lal Badshah, Noreen Khan, Lubna Ghani, Benjamin Gabriel Poulson, Abdul-Hamid Emwas, Mariusz Jaremko

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 540 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
540citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

540 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effects of flavonoids on atherosclerosis in ApoEFrontiers in pharmacology · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Phytochemical Characterization ofMolecules (Basel, Switzerland) · 2026
    Article
  15. Article
  16. Review
  17. Review
  18. RSC advances · 2026
    Article
  19. Article
  20. Article

480 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asad UllahDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.ORCID 0000-0002-0142-8565
Sidra MunirDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.ORCID 0000-0002-0976-0554
Syed Lal BadshahDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.ORCID 0000-0002-0229-1425
Noreen KhanDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.
Lubna GhaniDepartment of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, Azad Kashmir 13230, Pakistan.
Benjamin Gabriel PoulsonDivision of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.ORCID 0000-0001-8149-9023
Abdul-Hamid EmwasCore Labs, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.ORCID 0000-0002-9231-3850
Mariusz JaremkoDivision of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.

Indexed as

Alzheimer DiseaseAnimalsAntifungal AgentsAnti-Inflammatory AgentsAntimalarialsAntineoplastic AgentsAntioxidantsAntiviral AgentsCardiovascular SystemFlavonoidsHumansHypoglycemic AgentsMiceNervous SystemNeuronsNeuroprotective AgentsAntifungal AgentsAnti-Inflammatory AgentsAntimalarialsAntineoplastic AgentsAntioxidantsAntiviral AgentsFlavonoidsHypoglycemic AgentsNeuroprotective AgentsPlant ExtractsPolyphenolsQuercetinantioxidativeflavonoidsneuroprotectivepolyphenolsquercetin

Identifiers

PMID33187049
PMCPMC7697716

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.