Evidence map›Paper›PMID 33188073›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

IL-18 Responsiveness Defines Limitations in Immune Help for Specialized FcRγ

Renee R Anderko, Charles R Rinaldo, Robbie B Mailliard

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. NK cells in HPV-related tumorigenesis: mechanisms and clinical applications.Frontiers in cellular and infection microbiology · 2025
    Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Renee R AnderkoDepartment of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA 15261; and.ORCID 0000-0003-1964-3404
Charles R RinaldoDepartment of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA 15261; and.ORCID 0000-0002-9194-3164
Robbie B MailliardDepartment of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA 15261; and rbm19@pitt.edu.ORCID 0000-0001-5501-503X
University of Pittsburgh · US

Funding

University of Pittsburgh Multicenter AIDS Cohort Study (MACS)U01AI035041 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARTINSON, JEREMY JAMES, RINALDO, CHARLES R · 1993 to 2018
$71.4M
PITT AIDS RESEARCH TRAINING PROGRAMT32AI065380 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BARRATT-BOYES, SIMON M · 2005 to 2020
$3.2M
Programming Dendritic Cells to Expose the Persistent HIV-1 Latent Reservoir for Immune TargetingR21AI131763 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAILLIARD, ROBBIE B · 2017 to 2018
$429k
Replication Competent HIV-1 in Blood and TissuesR21AI138716 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAILLIARD, ROBBIE B · 2018 to 2019
$426k
NIAID NIH HHS R21 AI131763NIAID NIH HHS R21 AI138716NIAID NIH HHS T32 AI065380NIAID NIH HHS U01 AI035041
6 · The paper itself

Abstract

Despite being prolific innate killers, NK cells are also key helper cells in antiviral defense, influencing adaptive immune responses via interactions with dendritic cells (DCs). In addition to causing NK cell dysfunction, HIV-1 infection contributes to the expansion of a rare population of NK cells deficient in FcRγ (FcRγ

Indexed as

Antigens, CDDendritic CellsHIV-1HIV InfectionsHumansInterleukin-18Killer Cells, NaturalMaleReceptors, FcT-Lymphocytes, Helper-InducerAntigens, CDIL18 protein, humanInterleukin-18Receptors, Fc

Identifiers

PMID33188073
PMCPMC7725987
OpenAlexW3100715170

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.