Evidence map›Paper›PMID 33188227›Full record

ArticleScientific reports2020

Beneficial effects of daytime high-intensity light exposure on daily rhythms, metabolic state and affect.

Carmel Bilu, Haim Einat, Paul Zimmet, Vicktoria Vishnevskia-Dai, Noga Kronfeld-Schor

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carmel BiluSchool of Zoology, Tel-Aviv University, Tel Aviv, Ramat Aviv, Israel.
Haim EinatSchool of Behavioral Sciences, Tel Aviv-Yaffo Academic College, Tel-Aviv, Israel.
Paul ZimmetDepartment of Medicine, Monash University, Melbourne, VIC, Australia.
Vicktoria Vishnevskia-DaiOcular Oncology and Autoimmune Service, The Goldschleger Eye Institute, The Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Noga Kronfeld-SchorSchool of Zoology, Tel-Aviv University, Tel Aviv, Ramat Aviv, Israel. nogaks@tauex.tau.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the importance of the circadian system to health and well-being is extensively studied, the role of daylight exposure in these interactions is relatively poorly understood. Here we show, using a diurnal animal model naturally exposed to daylight, that daily morning exposure to 3000 lux, full spectrum electric light has beneficial health effects. Compared with controls, sand rats (Psammomys obesus) subjected to morning light treatment demonstrate daily rhythms with high peak to trough difference in activity, blood glucose levels and per2 gene expression in the suprachiasmatic nucleus, pre-frontal cortex, kidney and liver. The treated animals were also healthier, being normoglycemic, having higher glucose tolerance, lower body and heart weight and lower anxiety- and depression-like behavior. Our results suggest that exposure to high intensity light is important for the proper function of the circadian system and well-being, and are important in face of human's low exposure to daylight and extensive use of artificial light at night.

Indexed as

LightAnimalsAnxietyBlood GlucoseCataractCircadian RhythmDisease Models, AnimalEnzyme-Linked Immunosorbent AssayGerbillinaeMalePeriod Circadian ProteinsPhotoperiodSuprachiasmatic NucleusBlood GlucosePeriod Circadian Proteins

Identifiers

PMID33188227
PMCPMC7666121

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.