Evidence map›Paper›PMID 33190216›Full record

ReviewDiabetes therapy : research, treatment and education of diabetes and related disorders2021

Risk Prediction of the Diabetes Missing Million: Identifying Individuals at High Risk of Diabetes and Related Complications.

Marc Evans, Angharad R Morgan, Dipesh Patel, Ketan Dhatariya, Sharlene Greenwood, Philip Newland-Jones, Debbie Hicks, Zaheer Yousef, Jim Moore, Bethany Kelly and 2 more

Abstract readReview
In one paragraph

Review in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Role of Primary Care Clinicians in the Management of Patients With Type 2 Diabetes and Cardiorenal Diseases.Clinical diabetes : a publication of the American Diabetes Association · 2022
    Article
  17. Review
  18. One Hundred Years of Insulin: Value Beyond Price in Type 2 Diabetes Mellitus.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marc EvansDiabetes Resource Centre, University Hospital Llandough, Cardiff, UK. marclyndon1@hotmail.com.
Angharad R MorganHealth Economics and Outcomes Research Ltd., Cardiff, UK.
Dipesh PatelDepartment of Diabetes, Division of Medicine, University College London, Royal Free NHS Trust, London, UK.
Ketan DhatariyaElsie Bertram Diabetes Centre, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.
Sharlene GreenwoodRenal Medicine, King's College Hospital, London, UK.
Philip Newland-JonesUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK.
Debbie HicksMedicus Health Partners, Enfield, London, UK.
Zaheer YousefWales Heart Research Institute, Cardiff University, Cardiff, UK.
Jim MooreStoke Road Surgery, Bishop's Cleeve, Cheltenham, UK.
Bethany KellySolent NHS Trust, Southampton, UK.
Sarah DaviesWoodlands Medical Centre, Cardiff, UK.
Umesh DashoraEast Sussex Healthcare NHS Trust, St Leonards-on-Sea, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early diagnosis and effective management of type 2 diabetes (T2D) are crucial in reducing the risk of developing life-changing complications such as heart failure, stroke, kidney disease, blindness and amputation, which are also associated with significant costs for healthcare providers. However, as T2D symptoms often develop slowly it is not uncommon for people to live with T2D for years without being aware of their condition-commonly known as the undiagnosed missing million. By the time a diagnosis is received, many individuals will have already developed serious complications. While the existence of undiagnosed diabetes has long been recognised, wide-reaching awareness among the general public, clinicians and policymakers is lacking, and there is uncertainty in how best to identify high-risk individuals. In this article we have used consensus expert opinion alongside the available evidence, to provide support for the diabetes healthcare community regarding risk prediction of the missing million. Its purpose is to provide awareness of the risk factors for identifying individuals at high, moderate and low risk of T2D and T2D-related complications. The awareness of risk predictors, particularly in primary care, is important, so that appropriate steps can be taken to reduce the clinical and economic burden of T2D and its complications.

Indexed as

Chronic kidney diseaseDiabetes-related complicationsHeart failureRisk predictionType 2 diabetes

Identifiers

PMID33190216
PMCPMC7843706

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.